Urban malaria may be spreading via the wind-here's why that's important.
Urban malaria may be spreading via the wind-here's why that's important.
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DOI：
10.1073/pnas.2301666120
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发表时间：
2023-05-02
影响因子：
11.1
通讯作者：
Linton, Y. -m.
中科院分区：
文献类型：
--
作者：
Lehmann, T.;Bamou, R.;Chapman, J. W.;Reynolds, D. R.;Armbruster, P. A.;Dao, A.;Yaro, A. S.;Burkot, T. R.;Linton, Y. -m.
疟疾仍然是非洲最重要的病媒传播疾病，每年有超过590，000人死亡（1）。虽然到目前为止，非洲的疟疾主要是一个农村问题，但最近入侵性亚洲城市媒介斯氏按蚊的建立和扩张可能会彻底改变非洲的疾病风险状况。城市疟疾将成为更大的威胁（2-6）。与所有其他非洲疟疾病媒不同的是，一个。斯氏蚊幼虫在人类住所附近的容器栖息地（例如，废弃的轮胎或水槽）中茁壮成长，类似于城市黄热病蚊子埃及伊蚊。因此，非洲大陆迅速扩大的特大城市（如金沙萨和拉各斯）以及大都市（如喀土穆和阿比让）的人口现在更容易受到疟疾的影响（2，3，5，6）。很难夸大这种范式转变对公共卫生的重要性（4-6）。现有的监测和病媒控制策略不足以迅速转向解决城市，容器繁殖的按蚊，这种看似微小的病媒生态变化可能最终破坏横贯大陆的疟疾消除进展，在过去的三十年里，疟疾的负担已经大大减少（6）。stephensi进入非洲之角通过人为媒介的运输，船舶或可能的飞机（2，3，7，8）。这种假设很可能源于第一次发现的一个。非洲的stephensi距离吉布提港约20公里，并受到常见入侵物种传播模式的影响
Malaria remains the most important vector-borne disease in Africa, with over 590,000 deaths annually (1). Although until now, malaria in Africa has been primarily a rural problem, the recent establishment and expansion of the invasive urban Asian vector Anopheles stephensi will likely drastically change Africa’s disease risk landscape. Urban malaria will become a bigger threat (2–6). Unlike all other African malaria vectors, An. stephensi larvae thrive in container habitats (eg, abandoned tires or cisterns) near human dwellings, similar to the urban yellow fever mosquito, Aedes aegypti. Thus, human populations in the continent’s rapidly expanding megacities, such as Kinshasa and Lagos, and metropolises, such as Khartoum and Abidjan, are now more vulnerable to malaria (2, 3, 5, 6). It is hard to overstate the public health importance of this paradigm shift (4–6). Existing surveillance and vector-control strategies are ill-equipped to rapidly pivot to tackle urban, container-breeding Anopheles, and this seemingly minor change in vector ecology may ultimately derail transcontinental malaria elimination progress, which has achieved dramatic reductions in malaria’s burden over the past three decades (6).Currently, there’sa widely accepted hypothesis that people unwittingly imported An. stephensi into the Horn of Africa via human-mediated transport, on ships or possibly airplanes (2, 3, 7, 8). This supposition most likely stems from the first discovery of An. stephensi in Africa being about 20 kilometers from the port of Djibouti, and influenced by the established mode of spread of common invasives
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影响因子：
3.2
作者：
Carter TE;Yared S;Getachew D;Spear J;Choi SH;Samake JN;Mumba P;Dengela D;Yohannes G;Chibsa S;Murphy M;Dissanayake G;Flately C;Lopez K;Janies D;Zohdy S;Irish SR;Balkew M
通讯作者：
Balkew M
影响因子：
3.2
作者：
Balkew, Meshesha;Mumba, Peter;Carter, Tamar E.
通讯作者：
Carter, Tamar E.
影响因子：
2.1
作者：
Benedict, Mark Q.;Levine, Rebecca S.;Lounibos, L. Philip
通讯作者：
Lounibos, L. Philip
影响因子：
64.8
作者：
Huestis, Diana L.;Dao, Adama;Lehmann, Tovi
通讯作者：
Lehmann, Tovi
影响因子：
2.7
作者：
Ahmed, Ayman;Irish, Seth R.;Tadesse, Fitsum G.
通讯作者：
Tadesse, Fitsum G.