Potential Risks Associated with Japanese Encephalitis Prevalence in Shandong Province, China
Potential Risks Associated with Japanese Encephalitis Prevalence in Shandong Province, China
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中国山东省日本脑炎流行的潜在风险
DOI：
10.1089/vbz.2018.2416
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发表时间：
2019-05
期刊：
影响因子：
--
通讯作者：
Gong Maoqing
中科院分区：
文献类型：
--
作者：
Shi Qiqi;Song Xiao;Lv Yeyuan;Huang Xiaodan;Kou Jingxuan;Wang Huai Wei;Zhang Haobing;Cheng Peng;Gong Maoqing
摘要日本脑炎（JE）是由日本脑炎病毒（JEV）引起的一种人畜共患、媒介传播的嗜神经疾病，是亚洲病毒性脑炎的主要病因。乙脑病毒通过蚊虫传播给人类，其主要传播媒介是三带喙库蚊。蚊虫采集地点为山东省微山县韩庄镇、济宁市太白湖和东平湖。采用成蚊进行拟除虫菊酯类杀虫剂抗性生物测定。残雪。汉庄镇和东平湖三带喙库蚊和淡色库蚊种群对拟除虫菊酯类杀虫剂均有抗性，太白湖种群对拟除虫菊酯类杀虫剂均有初步抗性。在汉庄镇，黄花蒿种群也出现了抗性，而在太白湖，抗性刚刚开始。收集鉴定蚊虫16711只，分346个池进行乙脑病毒检测。残雪。三带喙蚊具有地方性优势。总体而言，135个Cx池中有31个（22.96个）。三带喙蚊乙脑病毒阳性。Cx的总体最大似然估计。三带喙库蚊、淡色库蚊和Cq。黄花菌的总感染率分别为5.29/1000（95%可信区间3.67 ~ 7.42）、1.60/1000 （95% CI = 0.82 ~ 2.85）和6.39/1000 （95% CI = 0.39 ~ 32.23）。各区合计感染率差异无统计学意义。对拟除虫菊酯类杀虫剂的抗药性增加了蚊媒控制的难度，尤其是对乙瘟阳性蚊媒的控制难度。鉴于乙脑传播媒介的变化，蚊虫种类的时空多样性和动态变化、杀虫剂耐药性和全球变暖都有可能促进乙脑向人类传播。
Abstract Japanese encephalitis (JE), which is caused by the Japanese encephalitis virus (JEV), is a zoonotic, vector-borne neurotropic disease that remains a major cause of viral encephalitis in Asia. JEV is spread to humans through mosquitoes, and its primary transmission vector is Culex tritaeniorhynchus. Mosquitoes were sampled from three collection sites: Hanzhuang town in Weishan County, Taibai Lake in Jining city, and Dongping Lake in Shandong Province, China. Pyrethroid insecticide resistance bioassays were conducted using adult mosquitoes. Cx. tritaeniorhynchus and C. pipiens pallens populations in Hanzhuang town and Dongping Lake showed resistance to pyrethroid insecticides, and populations in Taibai Lake showed incipient resistance. Coquillettidia ochracea populations in Hanzhuang town presented resistance as well, while in Taibai Lake, resistance was incipient. A total of 16,711 mosquitoes were collected, identified, and divided into 346 pools for JEV testing. Cx. tritaeniorhynchus had the advantage of being a local mosquito species. Overall, 31 (22.96) of the 135 pools of Cx. Tritaeniorhynchus were positive for JEV. The overall maximum likelihood estimates of Cx. tritaeniorhynchus, C. pipiens pallens, and Cq. ochracea indicated pooled infection rates of 5.29/1000 mosquitoes (95% confidence interval [CI] = 3.67–7.42), 1.60/1000 mosquitoes (95% CI = 0.82–2.85), and 6.39/1000 mosquitoes (95% CI = 0.39–32.23), respectively. There were no significant differences in the pooled infection rates between the districts. The resistance to pyrethroids has increased the difficulty in controlling the mosquito vectors, especially JEV-positive mosquitoes. Given the changes in the JEV transmission vectors, the spatial and temporal diversity and the dynamic variety of mosquito species, insecticide resistance and global warming have the potential to facilitate the transmission of JE to humans.
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2013年，中国爆发期间，蚊子中日本脑炎病毒的分子流行病学。
影响因子：
4.6
作者：
Tao Z;Liu G;Wang M;Wang H;Lin X;Song L;Wang S;Wang H;Liu X;Cui N;Song Y;Xu A
通讯作者：
Xu A
影响因子：
3.2
作者：
Kamgang B;Marcombe S;Chandre F;Nchoutpouen E;Nwane P;Etang J;Corbel V;Paupy C
通讯作者：
Paupy C
DOI：
10.1016/s0749-0739(17)30096-2
发表时间：
2000-12-01
影响因子：
1.1
作者：
Ellis, PM;Daniels, PW;Banks, DJ
通讯作者：
Banks, DJ
影响因子：
1.7
作者：
Chuaycharoensuk, Thipwara;Juntarajumnong, Waraporn;Chareonviriyaphap, Theeraphap
通讯作者：
Chareonviriyaphap, Theeraphap
DOI：
10.1007/978-1-4419-1108-7_18
发表时间：
2010-01-01
期刊：
VACCINES: A BIOGRAPHY
影响因子：
--
作者：
Halstead, Scott B.
通讯作者：
Halstead, Scott B.