Insecticide susceptibility of Aedes aegypti and Aedes albopictus in Central Africa.
Insecticide susceptibility of Aedes aegypti and Aedes albopictus in Central Africa.
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DOI：
10.1186/1756-3305-4-79
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发表时间：
2011-05-15
影响因子：
3.2
通讯作者：
Paupy C
中科院分区：
文献类型：
--
作者：
Kamgang B;Marcombe S;Chandre F;Nchoutpouen E;Nwane P;Etang J;Corbel V;Paupy C
埃及伊蚊（Linnaeus，1762）和白纹伊蚊（Skuse，1894）是全世界登革热（DENV）和基孔肯雅（CHIKV）病毒的主要媒介。由于DENV和CHIKV仍然没有疫苗或特异性治疗方法，病媒控制仍然是预防和疫情控制的基石。不幸的是，病媒控制计划面临着操作挑战，蚊子在世界上的几个地区对常用杀虫剂产生抗药性。在整个中部非洲，没有最近的数据，因为引进/到达的Ae病媒物种的敏感/耐药状态。白纹伊蚊在这个地区因此，我们研究了这两种主要病媒对非洲常用杀虫剂的抗药性水平。埃及伊蚊Aedes aegypti和Ae.在喀麦隆（加鲁阿、贝尔图阿、雅温得、巴菲亚、布埃亚）和加蓬（利伯维尔）的六个城市地区对白纹伊蚊进行了采样。幼虫的生物测定，进行确定致死浓度（LC 50和LC 95）和电阻率（RR 50和RR 95）表明，这两个载体物种是敏感的Bti（苏云金芽孢杆菌变种以色列）和temephos。还使用世卫组织诊断检测试剂盒对成年人进行了生物测定，以评估对溴氰菊酯、滴滴涕、杀螟松和残杀威的表型抗性。这些实验表明，一个群体的Ae。aegypti（Libreville）和两个Ae.白纹伊蚊（布埃亚和雅温得）对滴滴涕具有耐药性（死亡率为36%至71%）。对溴氰菊酯的抗性也被怀疑在Ae。雅温得的白纹伊蚊（死亡率83%）。所有其他现场蚊种群对溴氰菊酯、DDT、杀螟松和残杀威敏感。与其他Ae相比，雅温得抗性群体中的敲低时间（Kdt 50和Kdt 95）没有增加。白纹伊蚊种群，这表明可能参与代谢抗性溴氰菊酯和滴滴涕。鉴于最近在中非登革热和基孔肯雅热疫情的增加，这些独特的比较数据的杀虫剂敏感性的Ae。埃及伊蚊和埃及伊蚊。白纹伊蚊可以帮助公共卫生部门设计更有效的病媒控制措施。
Aedes aegypti (Linnaeus, 1762) and Aedes albopictus (Skuse, 1894) are the main vectors of dengue (DENV) and chikungunya (CHIKV) viruses worldwide. As there is still no vaccine or specific treatment for DENV and CHIKV, vector control remains the cornerstone of prevention and outbreak control. Unfortunately, vector control programs are facing operational challenges with mosquitoes becoming resistant to commonly used insecticides in several areas through the world. Throughout Central Africa no recent data are available susceptible/resistant status of either vector species since the introduction/arrival of Ae. albopictus in this area. We therefore studied the level of resistance of these two major vectors to insecticides commonly used in Africa for mosquito control. Aedes aegypti and Ae. albopictus were sampled in six urban localities of Cameroon (Garoua, Bertoua, Yaoundé, Bafia, Buea) and Gabon (Libreville). Larval bioassays, carried out to determine the lethal concentrations (LC50 and LC95) and resistance ratios (RR50 and RR95) suggested that both vector species were susceptible to Bti (Bacillus thuringiensis var israeliensis) and temephos. Bioassays were also performed on adults using WHO diagnostic test kits to assess phenotypic resistance to deltamethrin, DDT, fenitrothion and propoxur. These experiments showed that one population of Ae. aegypti (Libreville) and two populations of Ae. albopictus (Buea and Yaoundé) were resistant to DDT (mortality 36% to 71%). Resistance to deltamethrin was also suspected in Ae. albopictus from Yaoundé (83% mortality). All other field mosquito populations were susceptible to deltamethrin, DDT, fenitrothion and propoxur. No increase in the knockdown times (Kdt50 and Kdt95) was noted in the Yaoundé resistant population compared to other Ae. albopictus populations, suggesting the possible involvement of metabolic resistance to deltamethrin and DDT. In view of the recent increase in dengue and chikungunya outbreaks in Central Africa, these unique comparative data on the insecticide susceptibility of Ae. aegypti and Ae. albopictus could help public health services to design more effective vector control measures.
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影响因子：
11.8
作者：
Leroy EM;Nkoghe D;Ollomo B;Nze-Nkogue C;Becquart P;Grard G;Pourrut X;Charrel R;Moureau G;Ndjoyi-Mbiguino A;De-Lamballerie X
通讯作者：
De-Lamballerie X
DOI：
10.1590/s0074-02762003000500020
发表时间：
2003-07-01
期刊：
Memórias do Instituto Oswaldo Cruz
影响因子：
--
作者：
Macoris, Maria de Lourdes G;Andrighetti, Maria Teresa M;Bracco, José Eduardo
通讯作者：
Bracco, José Eduardo
DOI：
10.1590/s0074-02762010000100019
发表时间：
2010-02-01
期刊：
Memórias do Instituto Oswaldo Cruz
影响因子：
--
作者：
Llinás, G Albrieu;Seccacini, E;Licastro, S
通讯作者：
Licastro, S
影响因子：
1.9
作者：
Brengues, C;Hawkes, NJ;Hemingway, J
通讯作者：
Hemingway, J
影响因子：
2.1
作者：
Kow, CY;Koon, LL;Yin, PF
通讯作者：
Yin, PF