Sentinel surveillance of influenza and other respiratory viruses, Brazil, 2000-2010.

Sentinel surveillance of influenza and other respiratory viruses, Brazil, 2000-2010.
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DOI:
10.1016/j.bjid.2012.09.001
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发表时间:
2013-01
影响因子:
3.4
通讯作者:
de Mello Freitas, Felipe Teixeira
de Mello Freitas, Felipe Teixeira
中科院分区:
医学4区
文献类型:
--
作者:
de Mello Freitas, Felipe Teixeira

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关于南美洲和巴西的流感和其他呼吸道病毒的流行病学数据很少。本研究的目的是总结巴西流感和其他呼吸道病毒监测系统的数据,并讨论病毒循环的模式。该系统的基础是在哨点检测流感样疾病病例,每周收集5份鼻咽分泌物样本,在州公共卫生实验室通过间接免疫荧光法对这些样本进行呼吸道病毒检测。对2000年至2010年的数据按地区、性别和年龄组进行了描述,并在阳性样本数量最多的两个州首府(一个来自东北部地区(马塞约),另一个来自南部地区(库里蒂巴))对每月流感检测与降雨量和温度数据进行了斯皮尔曼相关性分析。有3,291,946人因流感样疾病就诊;其中37,120人采集了样本,6421人检测呈阳性:1690例(26%)甲型流感,567例(9%)B流感,277例(4%)1型副流感,571例(9%)2型副流感,589例(9%)3型副流感,742例(12%)腺病毒,1985年(31%)为呼吸道合胞病毒。总体而言,呼吸道合胞病毒的活动在3月至6月增加,在流感活动高峰之前,从5月至8月,但存在区域差异。在马塞约,温度与流感检测之间的相关性较弱(ρ = 0.05),但降雨量与流感检测之间存在中度正相关(ρ = 0.36)。在库里蒂巴,气温和降雨量的下降与流感检测率的上升之间存在高度相关性(分别为ρ =-0.83和-0.78)。这些数据对于指导公共卫生控制措施非常重要,因为这是接种流感疫苗和使用抗病毒药物的最佳时间。
There are scanty data on the epidemiology of influenza and other respiratory viruses in South America and Brazil. The aim of this study was to summarize the data from the Brazilian surveillance system of influenza and other respiratory viruses and discuss the patterns of viral circulation. The system is based on detecting cases of influenza-like illness in sentinel sites and weekly collection of five nasopharyngeal secretions samples, which are processed in state public health laboratories for respiratory viruses by indirect immunofluorescence assay. Data from 2000 to 2010 were described over time, by region, gender, and age group, and an analysis of Spearman correlation was performed between monthly influenza detection and rainfall and temperature data in two state capitals with the highest number of positive samples, one from the northeast region (Maceió) and other from the southern region (Curitiba). There were 3,291,946 visits for influenza-like illness; of these, 37,120 had samples collected and 6421 tested positive: 1690 (26%) influenza A, 567 (9%) influenza B, 277 (4%) parainfluenza 1, 571 (9%) parainfluenza 2, 589 (9%) parainfluenza 3, 742 (12%) adenovirus, and 1985 (31%) respiratory syncytial virus. Overall, increased activity of respiratory syncytial virus was observed from March to June, preceding the peak of influenza activity, from May to August, but with regional differences. In Maceió, there was a weak correlation between temperature and influenza detection (ρ = 0.05), but a moderate positive correlation between rainfall and influenza detection (ρ = 0.36). In Curitiba, a high correlation was observed between the decrease in temperature and rainfall and the increase in influenza detection (ρ = −0.83 and −0.78 respectively). These data are important to guide public health control measures as the best time for influenza vaccination and use of antivirals.
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DOI: 10.1056/nejmoa0804877
发表时间: 2009-02-05
期刊: The New England journal of medicine
影响因子: --
作者:
Hall CB;Weinberg GA;Iwane MK;Blumkin AK;Edwards KM;Staat MA;Auinger P;Griffin MR;Poehling KA;Erdman D;Grijalva CG;Zhu Y;Szilagyi P
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DOI: 10.4269/ajtmh.2009.81.180
发表时间: 2009-07-01
影响因子: 3.3
作者:
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