The effect of incorrect scanning distance on boundary detection errors and macular thickness measurements by spectral domain optical coherence tomography: a cross sectional study.
The effect of incorrect scanning distance on boundary detection errors and macular thickness measurements by spectral domain optical coherence tomography: a cross sectional study.
复制标题
DOI：
10.1186/1471-2415-14-148
复制
发表时间：
2014-11-27
影响因子：
2
通讯作者：
Somfai GM
中科院分区：
文献类型：
--
作者：
Varga BE;Tátrai E;Cabrera DeBuc D;Somfai GM
研究扫描距离对谱域光学相干断层扫描 (SD-OCT) 视网膜边界检测误差 (RBDE) 和视网膜厚度测量的影响。使用 RTVue SD-OCT 检查健康受试者的 10 只眼睛、糖尿病性黄斑水肿 (DME) 的 10 只眼睛和新生血管性年龄相关性黄斑变性 (AMD) 的 10 只眼睛。连续两次使用 MM5 协议来扫描黄斑。对于第一个会话，设备设置为距离眼睛 3.5 厘米，以便在低眼底图像质量（次优设置）的情况下获得可检测信号，而在第二个会话中，设备距离眼睛设置为 2.5 厘米，以获得高质量的眼底图像。记录信号强度（SSI）值。每次检查的十次扫描计算视网膜边界检测错误（RBDE）的分数。记录整个扫描以及周边 1.0 毫米区域的 RBDE 分数。比较两个疗程之间的 RBDE 评分、区域视网膜厚度值和 SSI 值。还检查了 SSI 和 RBDE 数量之间的相关性。与最佳设置相比，次优设置下的 SSI 显着较低（分别为 63.9±12.0 与 68.3±12.2，p = 0.001），并且“全眼”组以及健康受试者和 DME 眼睛组中，次优设置下的 RBDE 数量显着较高（9.1±6.5 与 6.8±6.3，p = 0.007；分别为 4.4±2.6 与 2.5±1.6，p = 0.035 和 9.7±3.3 与 5.1±3.7，p = 0.008。对于这些群体，SSI 和 RBDE 数量之间存在显着负相关。在 AMD 组中，RBDE 的数量明显高于其他组，并且最佳和次优设置之间的 RBDE 没有差异，且误差与 SSI 无关。在“全眼”组和 DME 亚组中，最佳设置下的外周 RBDE 显着减少（分别为 2.7±2.6 与 4.2±2.8，p = 0.001 和 1.4±1.7 与 4.1±2.2，p = 0.007）。两种设置下的视网膜厚度仅在 DME 的外上方区域存在显着差异。最佳距离设置可改善 SD-OCT SSI，同时减少 RBDE，而视网膜厚度测量与扫描距离无关。
To investigate the influence of scan distance on retinal boundary detection errors (RBDEs) and retinal thickness measurements by spectral domain optical coherence tomography (SD-OCT). 10 eyes of healthy subjects, 10 eyes with diabetic macular edema (DME) and 10 eyes with neovascular age-related macular degeneration (AMD) were examined with RTVue SD-OCT. The MM5 protocol was used in two consecutive sessions to scan the macula. For the first session, the device was set 3.5 cm from the eye in order to obtain detectable signal with low fundus image quality (suboptimal setting) while in the second session a distance of 2.5 cm was set with a good quality fundus image. The signal strength (SSI) value was recorded. The score for retinal boundary detection errors (RBDE) was calculated for ten scans of each examination. RBDE scores were recorded for the whole scan and also for the peripheral 1.0 mm region. RBDE scores, regional retinal thickness values and SSI values between the two sessions were compared. The correlation between SSI and the number of RBDEs was also examined. The SSI was significantly lower with suboptimal settings compared to optimal settings (63.9±12.0 vs. 68.3±12.2, respectively, p = 0.001) and the number of RBDEs was significantly higher with suboptimal settings in the “all-eyes” group along with the group of healthy subjects and eyes with DME (9.1±6.5 vs. 6.8±6.3, p = 0.007; 4.4±2.6 vs. 2.5±1.6, p = 0.035 and 9.7±3.3 vs. 5.1±3.7, p = 0.008, respectively). For these groups, significant negative correlation was found between the SSI and the number of RBDEs. In the AMD group, the number of RBDEs was markedly higher compared to the other groups and there was no difference in RBDEs between optimal and suboptimal settings with the errors being independent of the SSI. There were significantly less peripheral RBDEs with optimal settings in the “all-eyes” group and the DME subgroup (2.7±2.6 vs. 4.2±2.8, p = 0.001 and 1.4±1.7 vs. 4.1±2.2, p = 0.007, respectively). Retinal thickness in the two settings was significantly different only in the outer-superior region in DME. Optimal distance settings improve SD-OCT SSI with a decrease in RBDEs while retinal thickness measurements are independent of scanning distance.
登录
查看更多内容
影响因子：
13.7
作者：
Garas, Anita;Vargha, Peter;Hollo, Gabor
通讯作者：
Hollo, Gabor
影响因子：
13.7
作者：
Hee, MR;Baumal, CR;Fujimoto, JG
通讯作者：
Fujimoto, JG
DOI：
10.1136/bjophthalmol-2011-300044
发表时间：
2012-04
期刊：
The British journal of ophthalmology
影响因子：
--
作者：
Folio LS;Wollstein G;Ishikawa H;Bilonick RA;Ling Y;Kagemann L;Noecker RJ;Fujimoto JG;Schuman JS
通讯作者：
Schuman JS
影响因子：
4.2
作者：
Chen, TC;Cense, B;de Boer, JF
通讯作者：
de Boer, JF
影响因子：
--
作者：
Huang, Jingjing;Liu, Xing;Sadda, Srinivas
通讯作者：
Sadda, Srinivas