Multilayer Soft Photolithography Fabrication of Microfluidic Devices Using a Custom-Built Wafer-Scale PDMS Slab Aligner and Cost-Efficient Equipment.
Multilayer Soft Photolithography Fabrication of Microfluidic Devices Using a Custom-Built Wafer-Scale PDMS Slab Aligner and Cost-Efficient Equipment.
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DOI:
10.3390/mi13081357
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发表时间:
2022-08-20
期刊:
影响因子:
3.4
通讯作者:
Ahsan, Fakhrul
中科院分区:
文献类型:
--
作者:
Nguyen, Trieu;Sarkar, Tanoy;Tran, Tuan;Moinuddin, Sakib M.;Saha, Dipongkor;Ahsan, Fakhrul
We present a robust, low-cost fabrication method for implementation in multilayer soft photolithography to create a PDMS microfluidic chip with features possessing multiple height levels. This fabrication method requires neither a cleanroom facility nor an expensive UV exposure machine. The central part of the method stays on the alignment of numerous PDMS slabs on a wafer-scale instead of applying an alignment for a photomask positioned right above a prior exposure layer using a sophisticated mask aligner. We used a manual XYZR stage attached to a vacuum tweezer to manipulate the top PDMS slab. The bottom PDMS slab sat on a rotational stage to conveniently align with the top part. The movement of the two slabs was observed by a monocular scope with a coaxial light source. As an illustration of the potential of this system for fast and low-cost multilayer microfluidic device production, we demonstrate the microfabrication of a 3D microfluidic chaotic mixer. A discussion on another alternative method for the fabrication of multiple height levels is also presented, namely the micromilling approach.
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DOI:
10.3390/bios12080587
发表时间:
2022-08-01
期刊:
Biosensors
影响因子:
--
作者:
通讯作者:
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影响因子:
6.2
作者:
Mohanty, Soumyaranjan;Alm, Martin;Emneus, Jenny
通讯作者:
Emneus, Jenny
影响因子:
6.1
作者:
Araci, Ismail Emre;Quake, Stephen R.
通讯作者:
Quake, Stephen R.
影响因子:
8.4
作者:
Aghvami, S. Ali;Opathalage, Achini;Fraden, Seth
通讯作者:
Fraden, Seth
影响因子:
2.4
作者:
DasGupta, Debabrata;Mondal, Pranab Kumar;Chakraborty, Suman
通讯作者:
Chakraborty, Suman