Characterization of the Sexually Dimorphic fruitless Neurons That Regulate Copulation Duration.
Characterization of the Sexually Dimorphic fruitless Neurons That Regulate Copulation Duration.
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DOI:
10.3389/fphys.2018.00780
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发表时间:
2018
影响因子:
4
通讯作者:
Leung AK
中科院分区:
文献类型:
--
作者:
Jois S;Chan YB;Fernandez MP;Leung AK
Male courtship in Drosophila melanogaster is a sexually dimorphic innate behavior that is hardwired in the nervous system. Understanding the neural mechanism of courtship behavior requires the anatomical and functional characterization of all the neurons involved. Courtship involves a series of distinctive behavioral patterns, culminating in the final copulation step, where sperms from the male are transferred to the female. The duration of this process is tightly controlled by multiple genes. The fruitless (fru) gene is one of the factors that regulate the duration of copulation. Using several intersectional genetic combinations to restrict the labeling of GAL4 lines, we found that a subset of a serotonergic cluster of fru neurons co-express the dopamine-synthesizing enzyme, tyrosine hydroxylase, and provide behavioral and immunological evidence that these neurons are involved in the regulation of copulation duration.
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