A Systematic Review of Exercise Systematic Reviews in the Cancer Literature (2005-2017).

A Systematic Review of Exercise Systematic Reviews in the Cancer Literature (2005-2017).
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DOI:
10.1016/j.pmrj.2017.07.074
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发表时间:
2017-09
期刊:
PM & R : the journal of injury, function, and rehabilitation
影响因子:
--
通讯作者:
Welsh J
Welsh J
中科院分区:
其他
文献类型:
--
作者:
Stout NL;Baima J;Swisher AK;Winters-Stone KM;Welsh J

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证据支持癌症患者运动的益处,然而,缺乏关于运动时间,频率,持续时间和强度的临床决策的具体指导。需要努力优化癌症人群运动的临床建议。通过对癌症运动文献中现有系统性综述的系统性综述,汇总有关运动益处的信息。PubMed、CINAHL Plus、Scopus、Web of Science、EMBASE。运动锻炼对成年癌症人群影响的系统综述和荟萃分析。两个作者团队审查了302篇摘要,其中93篇选择进行全文审查。共分析了53项研究。评估系统评价的测量工具(AMSTAR©)被用作评价的质量指标。使用皮科格式(参与者、干预、比较、结局)提取信息。报告了描述性结果。平均AMSTAR©评分= 7.66 / 11(±2.04)表明系统评价的质量中等。在癌症治疗之前,期间和之后,运动对所有癌症类型以及各种癌症相关损伤都是有益的。中度至剧烈运动是改善身体机能和减轻癌症相关损害的最佳运动强度水平。治疗性运动有益于管理治疗副作用,可以增强对癌症治疗的耐受性,并改善功能结果。有监督的锻炼比无监督的锻炼产生了上级效益。严重不良事件并不常见。报告了基于运动的运动干预结果。由于系统性综述中存在显著异质性,因此未计算综述间的汇总效应分析。研究结果没有考虑在晚期癌症或儿科人群中进行运动。运动促进临床,功能和某些人群的生存结果的显着改善,无论癌症类型如何,都可以推荐运动。尽管总体上是安全的,但应对患者进行筛查并采取适当的预防措施。需要努力加强临床试验报告的统一性,制定临床实践指南,并将运动和康复服务纳入癌症提供系统。
Evidence supports the benefits of exercise for cancer patients, however, specific guidance for clinical decision making regarding exercise timing, frequency, duration and intensity is lacking. Efforts are needed to optimize clinical recommendations for exercise in the cancer population. To aggregate information regarding the benefit of exercise through a systematic review of existing systematic reviews in the cancer exercise literature. PubMed, CINAHL Plus, Scopus, Web of Science, EMBASE. Systematic reviews and meta-analyses of the impact of movement-based exercise on the adult cancer population. Two author teams reviewed 302 abstracts for inclusion with 93 selected for full text review. 53 studies were analyzed. A Measurement Tool to Assess Systematic Reviews (AMSTAR©) was used as a quality measure of the reviews. Information was extracted using the PICO format (participants, intervention, comparison, outcomes). Descriptive findings are reported. Mean AMSTAR© score = 7.66 / 11 (±2.04) suggests moderate quality of the systematic reviews. Exercise is beneficial before, during, and after cancer treatment, across all cancer types, and for a variety of cancer-related impairments. Moderate to vigorous exercise is the best level of exercise intensity to improve physical function and mitigate cancer-related impairments. Therapeutic exercises are beneficial to manage treatment side effects, may enhance tolerance to cancer treatments, and improve functional outcomes. Supervised exercise yielded superior benefits versus unsupervised. Serious adverse events were not common. Movement-based exercise intervention outcomes are reported. No analysis of pooled effects was calculated across reviews due to significant heterogeneity within the systematic reviews. Findings do not consider exercise in advanced cancers or pediatric populations. Exercise promotes significant improvements in clinical, functional, and in some populations, survival outcomes and can be recommended regardless of the type of cancer. Although generally safe, patients should be screened and appropriate precautions taken. Efforts to strengthen uniformity in clinical trial reporting, develop clinical practice guidelines, and integrate exercise and rehabilitation services into the cancer delivery system are needed.
DOI: 10.1186/s12885-016-2733-z
发表时间: 2016-08-25
期刊: BMC cancer
影响因子: 3.8
作者:
Meneses-Echávez JF;Jiménez EG;Río-Valle JS;Correa-Bautista JE;Izquierdo M;Ramírez-Vélez R
通讯作者: Ramírez-Vélez R
DOI: 10.1136/bmj.e70
发表时间: 2012-01-30
期刊: BMJ (Clinical research ed.)
影响因子: --
作者:
Fong DY;Ho JW;Hui BP;Lee AM;Macfarlane DJ;Leung SS;Cerin E;Chan WY;Leung IP;Lam SH;Taylor AJ;Cheng KK
通讯作者: Cheng KK
DOI: 10.1097/01.hjr.0000173106.68485.b7
发表时间: 2005-08-01
影响因子: --
作者:
Hambrecht, R;Schulze, PC;Schuler, G
通讯作者: Schuler, G
DOI: 10.1142/s0192415x02000636
发表时间: 2002-01-01
影响因子: 5.7
作者:
Chao, YFC;Chen, SY;Lai, JS
通讯作者: Lai, JS
DOI: 10.1186/1471-2407-12-412
发表时间: 2012-09-18
期刊: BMC cancer
影响因子: 3.8
作者:
Cramer H;Lange S;Klose P;Paul A;Dobos G
通讯作者: Dobos G