Recognition tunneling measurement of the conductance of DNA bases embedded in self-assembled monolayers.

Recognition tunneling measurement of the conductance of DNA bases embedded in self-assembled monolayers.
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DOI:
10.1021/jp104792s
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发表时间:
2010-12-09
影响因子:
3.7
通讯作者:
Lindsay, Stuart
Lindsay, Stuart
中科院分区:
化学3区
文献类型:
--
作者:
Huang, Shuo;Chang, Shuai;He, Jin;Zhang, Peiming;Liang, Feng;Tuchband, Michael;Li, Shengqing;Lindsay, Stuart

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DNA碱基与金电极强烈相互作用,使得通过氢键结合的沃森克里克碱基对测量隧道电导的工作变得复杂。当碱基嵌入在自组装的烷烃硫醇单层中以最小化这些相互作用时,新的特征出现在隧穿数据中。这些新的功能跟踪密度泛函计算的预测相当不错,这表明它们反映了通过氢键碱基对的隧道电导。
The DNA bases interact strongly with gold electrodes, complicating efforts to measure the tunneling conductance through hydrogen-bonded Watson Crick base pairs. When bases are embedded in a self-assembled alkane-thiol monolayer to minimize these interactions, new features appear in the tunneling data. These new features track the predictions of density-functional calculations quite well, suggesting that they reflect tunnel conductance through hydrogen-bonded base pairs.
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