Surface modification of Ni-Ti alloys for stent application after magnetoelectropolishing.

Surface modification of Ni-Ti alloys for stent application after magnetoelectropolishing.
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DOI:
10.1016/j.msec.2015.01.009
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发表时间:
2015-05
期刊:
Materials science & engineering. C, Materials for biological applications
影响因子:
--
通讯作者:
Rokicki R
Rokicki R
中科院分区:
其他
文献类型:
--
作者:
Gill P;Musaramthota V;Munroe N;Datye A;Dua R;Haider W;McGoron A;Rokicki R

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在过去的十年中,对新型植入材料的不断需求和支架应用的多学科设计方法已经大大扩展。这些植入材料的生物相容性取决于其表面特性,如形态、表面化学、粗糙度、表面电荷和润湿性。这些表面特性可以直接影响材料的耐腐蚀性和生物过程,如内皮化。表面形貌影响钝化氧化物的热力学稳定性,从而影响钝化合金的耐蚀性。电磁抛光(MEP)可以改变表面膜的形态和组成,从而有助于提高镍钛诺合金的耐腐蚀性。利用扫描电镜(SEM)和x射线光电子能谱(XPS)分析了MEP镍钛诺合金的表面特征。通过接触角测试合金的润湿性,纳米压痕测试合金的力学性能。合金元素的加入改善了合金的力学性能。采用循环动电位极化试验测定其腐蚀敏感性。进一步,测试了合金的细胞毒性和内皮细胞的细胞生长情况。经MEP表面处理的合金的耐蚀性和细胞活力均有所提高。
The constant demand for new implant materials and the multidisciplinary design approaches for stent applications have expanded vastly over the past decade. The biocompatibility of these implant materials is a function of their surface characteristics such as morphology, surface chemistry, roughness, surface charge and wettability. These surface characteristics can directly influence the material's corrosion resistance and biological processes such as endothelialization. Surface morphology affects the thermodynamic stability of passivating oxides, which renders corrosion resistance to passivating alloys. Magnetoelectropolishing (MEP) is known to alter the morphology and composition of surface films, which assist in improving corrosion resistance of Nitinol alloys. This work aims at analyzing the surface characteristics of MEP Nitinol alloys by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The wettability of the alloys was determined by contact angle measurements and the mechanical properties were assessed by Nanoindentation. Improved mechanical properties were observed with the addition of alloying elements. Cyclic potentiodynamic polarization tests were performed to determine the corrosion susceptibility. Further, the alloys were tested for their cytotoxicity and cellular growth with endothelial cells. Improved corrosion resistance and cellular viability were observed with MEP surface treated alloys.
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