Using Large-Scale Statistical Chinese Brain Template (Chinese2020) in Popular Neuroimage Analysis Toolkits.

Using Large-Scale Statistical Chinese Brain Template (Chinese2020) in Popular Neuroimage Analysis Toolkits.
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在流行的神经图像分析工具包中使用大规模统计中国人大脑模板(Chinese2020)

DOI:
10.3389/fnhum.2017.00414
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发表时间:
2017
影响因子:
2.9
通讯作者:
Li K
Li K
中科院分区:
医学3区
文献类型:
--
作者:
Shi L;Liang P;Luo Y;Liu K;Mok VCT;Chu WCW;Wang D;Li K

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鉴于中国人大脑的形态在统计上与高加索人的不同,迫切需要开发一种中国人的大脑模板,用于中国人的神经成像研究。基于多中心数据集,我们开发了一个统计的中文大脑模板,命名为Chinese2020(梁等人,2015)。这一新的中文脑图谱已经在解剖磁共振成像研究的脑归一化和分割方面得到了验证,并在http://www.chinese-brain-atlases.org/.上公开可用在我们之前的研究中,我们已经证明了该中文地图集在配准过程中表现出了较高的分割精度和相对较小的形状变形。由于功能图像的空间归一化主要基于解剖图像的分割和归一化,因此特定人群的脑图谱也应该更适合于涉及中国人群的功能研究。这份技术报告的目的是验证Chinese2020模板在功能神经成像研究中的表现,并证明对于中国人的研究,使用Chinese2010模板可以产生更有效的结果。本技术报告详细给出了在SPM软件中使用Chinese2020模板的步骤,并以手指敲击功能磁共振研究为例,论证了Chinese2020模板可以提高中国人群神经影像分析的性能。
Given that the morphology of Chinese brains statistically differs from that of Caucasian, there is an urgent need to develop a Chinese brain template for neuroimaging studies in Chinese populations. Based on a multi-center dataset, we developed a statistical Chinese brain template, named as Chinese2020 (Liang et al., 2015). This new Chinese brain atlas has been validated in brain normalization and segmentation for anatomical Magnetic Resonance Imaging (MRI) studies, and is publicly available at http://www.chinese-brain-atlases.org/. In our previous study, we have demonstrated this Chinese atlas showed higher accuracy in segmentation and relatively smaller shape deformations during registration. Because the spatial normalization of functional images is mainly based on the segmentation and normalization of anatomical image, the population-specific brain atlas should also be more appropriate for functional studies involving Chinese populations. The aim of this technology report is to validate the performance of Chinsese2020 template in functional neuroimaging studies, and demonstrated that for Chinese population studies, the use of the Chinese2010 template produces more valid results. The steps of how to use the Chinese2020 template in SPM software were given in details in this technology report, and based on an example of finger tapping fMRI study, this technology report demonstrated the Chinese2020 template could improve the performance of the neuroimaging analysis of Chinese populations.
基于2020年中国成年人多中心MRI数据集的脑图谱构建
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