On the link between the speckle free nature of optoacoustics and visibility of structures in limited-view tomography.
On the link between the speckle free nature of optoacoustics and visibility of structures in limited-view tomography.
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DOI：
10.1016/j.pacs.2016.10.001
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发表时间：
2016-12
期刊：
影响因子：
7.9
通讯作者：
Razansky, Daniel
中科院分区：
文献类型：
--
作者：
Dean-Ben, Xose Luis;Razansky, Daniel
与脉冲回波超声类似，光声成像通过超声波的飞行时间对光学吸收体的位置进行编码。然而，两种模式的信号生成机制是根本不同的，导致最佳图像形成策略之间的显着区别。虽然具有随机相位的背散射超声波的干扰导致超声图像中的斑点噪声，但斑点形成受到对应于各个源的光声响应之间的强相关性的阻碍。然而，当试图在有限视角断层几何结构下获取光声图像时，结构的可见性受到严重阻碍。在这篇教程文章中，我们系统地描述了光声信号产生和图像形成的基本原理，从单个次分辨率吸收体到连续吸收分布的物体。结果是相关的光声图像有限的视野下获得的情况下，适当的解释，也可以作为最佳设计的层析成像采集几何形状和图像形成策略的基础。
Similar to pulse-echo ultrasound, optoacoustic imaging encodes the location of optical absorbers by the time-of-flight of ultrasound waves. Yet, signal generation mechanisms are fundamentally different for the two modalities, leading to significant distinction between the optimum image formation strategies. While interference of back-scattered ultrasound waves with random phases causes speckle noise in ultrasound images, speckle formation is hindered by the strong correlation between the optoacoustic responses corresponding to individual sources. However, visibility of structures is severely hampered when attempting to acquire optoacoustic images under limited-view tomographic geometries. In this tutorial article, we systematically describe the basic principles of optoacoustic signal generation and image formation for objects ranging from individual sub-resolution absorbers to a continuous absorption distribution. The results are of relevance for the proper interpretation of optoacoustic images acquired under limited-view scenarios and may also serve as a basis for optimal design of tomographic acquisition geometries and image formation strategies.
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