The association between DSM-IV nicotine dependence and stressful life events in the National Epidemiologic Survey on Alcohol and Related Conditions.

The association between DSM-IV nicotine dependence and stressful life events in the National Epidemiologic Survey on Alcohol and Related Conditions.
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DOI:
10.1080/00952990802585430
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发表时间:
2009
期刊:
The American journal of drug and alcohol abuse
影响因子:
--
通讯作者:
Agrawal A
Agrawal A
中科院分区:
其他
文献类型:
--
作者:
Balk E;Lynskey MT;Agrawal A

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尼古丁依赖(ND)是一个普遍的公共卫生问题,也是可预防死亡的主要原因。应激性生活事件(SLEs)严重扰乱了经历这类事件的个体的生活,被认为是持续性ND的相关因素。虽然ND和SLES与其他变量的关系已经得到了广泛的研究,但很少有人同时对它们进行研究。在这项研究中,我们使用全国酒精和相关疾病流行病学调查(NESARC,N=43,093)2001-2002年数据集中的18,013名吸烟者的数据来检查在过去12个月中经历过SLE是否与在过去12个月中符合ND标准有关。在考虑各种协变量的同时,进行了Logistic回归分析。大多数SLEs与过去12个月的ND有关,即使在控制了贫困、精神和物质使用障碍以及既往ND病史之后(优势比1.35-2.20)。在过去12个月中,经历过一次以上系统性红斑狼疮的患者发生ND的几率要高得多。虽然这些数据不允许我们做出因果解释,但我们的结果表明SLE和ND之间存在联系。潜在地,患有SLEs的人可能会发现很难戒烟;或者,直接或通过相关风险(例如,生活在高危社区),吸烟可能会增加接触SLEs的可能性。
Nicotine dependence (ND) is a pervasive public health concern and a leading cause of preventable mortality. Stressful life events (SLEs), which severely disrupt the lives of individuals experiencing such events, have been posited as correlates of persisting ND. While both ND and SLEs have been studied extensively in relation to other variables, there are few instances in which they have been investigated in concert. In this study, we use data on 18,013 smokers from the 2001-2002 data set of the National Epidemiological Survey of Alcohol and Related Conditions (NESARC, N=43,093) to examine whether experiencing a SLE in the past 12 months was associated with meeting criteria for ND in the same past 12 months. Logistic regression analyses were conducted while accounting for a variety of covariates. A majority of the SLEs were associated with past 12 month ND, even after controlling for poverty, psychiatric and substance use disorders and a prior history of ND (odds-ratios 1.35-2.20). The rates of past 12 month ND were considerably greater in those experiencing more than one SLE. While these data do not allow us to make causal interpretations, our results suggest an association between SLE and ND. Potentially, individuals experiencing SLEs may find it difficult to quit smoking; alternatively, directly or via correlated risks (e.g. living in a high risk neighborhood), smoking may increase the likelihood of exposure to SLEs.
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