Subchondral trabecular bone integrity changes following ACL injury and reconstruction: a cohort study with a nested, matched case-control analysis.
Subchondral trabecular bone integrity changes following ACL injury and reconstruction: a cohort study with a nested, matched case-control analysis.
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DOI：
10.1016/j.joca.2018.02.905
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发表时间：
2018-06
影响因子：
7
通讯作者：
Tourville TW
中科院分区：
文献类型：
--
作者：
Birch CE;Mensch KS;Desarno MJ;Beynnon BD;Tourville TW
关于ACL损伤后骨结构变化的信息有限。本研究的目的是评价ACL损伤后内侧和外侧间室胫骨分形特征的差异，并描述这些值在ACL重建和恢复活动后如何变化。这是一项前瞻性队列研究，采用巢式病例对照分析。ACL损伤受试者和匹配的对照组在术前基线和ACL重建后平均46个月随访时进行评价。在水平和垂直方向上计算内侧和外侧感兴趣区域胫骨软骨下骨结构的系列分形维数（FD）。在内侧和外侧间室中，与对侧健康胫骨（内侧p<0.0001;外侧p<0.0001）和对照组（内侧p=0.01;外侧p<0.0001）相比，最终随访时ACL损伤受试者的垂直FD特征存在显著差异。同样，在外侧间室中，与对侧健康胫骨（p=0.003）和对照组（p<0.0001）相比，ACL损伤受试者在最终随访时的水平FD曲线存在显著差异。在基线或最终随访时，健康对照受试者内侧或外侧间室的FD无显著侧侧差异。在46个月随访时，与对侧健康膝关节和未受伤对照组相比，ACL损伤膝关节的分形维数特征显著不同，并显示出总体较低的FD特征。此外，本研究提供了健康对照组内侧和外侧FD值的第一个左右对称性数据。
There is limited information regarding changes in bone architecture following ACL injury. The objective of this study was to evaluate differences in tibial fractal signature in the medial and lateral compartments following ACL injury and describe how these values change following ACL-reconstruction and return to activity. This was a prospective cohort study with a nested case-control analysis. ACL-injured subjects and matched controls were evaluated at pre-surgical baseline and post ACL reconstruction follow-up at a mean of 46 months. Serial Fractal Dimensions (FD) of tibial subchondral bone architecture were calculated in medial and lateral regions of interest in the horizontal and vertical dimensions. In the medial and lateral compartments, there were significant differences in the vertical FD signature for ACL-injured subjects at final follow-up, when compared to the contralateral healthy tibia (medial p<0.0001; lateral p<0.0001) and the control group (medial p=0.01; lateral p<0.0001). Similarly, in the lateral compartment, there were significant differences in the horizontal FD profile for ACL-injured subjects at final follow-up, when compared to the contralateral healthy tibia (p=0.003) and the controls (p<0.0001). There were no significant side-to-side differences in FDs among healthy control subjects in the medial or lateral compartments at baseline or final follow-up. At 46-month follow-up, Fractal Dimension profiles are significantly different, and show an overall lower FD signature, for ACL-injured knees when compared to the contralateral healthy knee and uninjured controls. Additionally, this study provided the first side-to-side symmetry data of medial and lateral FD values in healthy controls.
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骨结构和解剖学在骨关节炎中的作用。
影响因子：
4.1
作者：
Baker-LePain, Julie C.;Lane, Nancy E.
通讯作者：
Lane, Nancy E.
影响因子：
7
作者：
Messent, EA;Ward, RJ;Buckland-Wright, C
通讯作者：
Buckland-Wright, C
影响因子：
7
作者：
Kraus, V. B.;Burnett, B.;Todman, M.
通讯作者：
Todman, M.
影响因子：
--
作者：
Kraus, Virginia Byers;Feng, Sheng;Charles, H. Cecil
通讯作者：
Charles, H. Cecil
DOI：
10.3109/14639239109012130
发表时间：
1991-04-01
期刊：
MEDICAL INFORMATICS
影响因子：
--
作者：
LYNCH, JA;HAWKES, DJ;BUCKLANDWRIGHT, JC
通讯作者：
BUCKLANDWRIGHT, JC