Neural mechanisms of motivated forgetting.
Neural mechanisms of motivated forgetting.
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DOI：
10.1016/j.tics.2014.03.002
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发表时间：
2014-06
影响因子：
19.9
通讯作者：
Hanslmayr, Simon
中科院分区：
文献类型：
--
作者：
Anderson, Michael C.;Hanslmayr, Simon
有动机地遗忘不想要的记忆会塑造我们对个人过去的记忆。动机性遗忘部分是通过对编码或提取的抑制控制来实现的。前额叶皮层减少海马和皮层的活动，以抑制记忆。动机性遗忘过程中的电生理活动涉及主动抑制。记忆控制的神经生物学模型可以告知对记忆的无序控制。并非所有的记忆都同样受意识的欢迎。人们会限制自己思考不愉快经历的时间，这一过程始于编码过程，但当后来的线索提醒某人回忆时，这一过程会继续下去。在这里，我们回顾了新兴的行为和神经影像学证据，抑制意识的不受欢迎的记忆，在编码或检索，是通过抑制控制过程介导的外侧前额叶皮层。这些机制与记忆中代表经验的神经结构相互作用，破坏支持保留的痕迹。因此，用于调节瞬间意识的机制引入了持久的偏见，在这些偏见中，经验仍然是可访问的。我们认为，遗忘理论忽视了意识的动机控制，忽略了一个强大的力量塑造我们的过去的保留。
Motivated forgetting of unwanted memories shapes what we retain of our personal past. Motivated forgetting is achieved in part by inhibitory control over encoding or retrieval. Prefrontal cortex reduces hippocampal and cortical activity to suppress memories. Electrophysiological activity during motivated forgetting implicates active inhibition. A neurobiological model of memory control can inform disordered control over memory. Not all memories are equally welcome in awareness. People limit the time they spend thinking about unpleasant experiences, a process that begins during encoding, but that continues when cues later remind someone of the memory. Here, we review the emerging behavioural and neuroimaging evidence that suppressing awareness of an unwelcome memory, at encoding or retrieval, is achieved by inhibitory control processes mediated by the lateral prefrontal cortex. These mechanisms interact with neural structures that represent experiences in memory, disrupting traces that support retention. Thus, mechanisms engaged to regulate momentary awareness introduce lasting biases in which experiences remain accessible. We argue that theories of forgetting that neglect the motivated control of awareness omit a powerful force shaping the retention of our past.
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影响因子：
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