The dynamic relationship between physical function and cognition in longitudinal aging cohorts.

The dynamic relationship between physical function and cognition in longitudinal aging cohorts.
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DOI:
10.1093/epirev/mxs004
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发表时间:
2013
影响因子:
5.5
通讯作者:
Hofer SM
Hofer SM
中科院分区:
医学3区
文献类型:
--
作者:
Clouston SA;Brewster P;Kuh D;Richards M;Cooper R;Hardy R;Rubin MS;Hofer SM

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平均而言,老年人比年轻人记得更少,走得更慢。一些研究人员认为,这在一定程度上是由于一个共同的生物学过程,其基础是与年龄相关的身体和认知功能的下降。直到最近才有纵向数据来分析这一说法。我们对2000年至2011年间发表的英语研究进行了系统回顾,以评估老年人群身体和认知功能变化率之间的关系。使用客观指标评估身体功能:步行速度,握力,椅子上升时间,火烈鸟站立时间和身体功能的汇总指标。认知能力的测量采用精神状态检查、流体认知和损伤诊断。结果取决于测量类型:握力的变化与精神状态的相关性更强,而步行速度的变化与流体认知的变化相关性更强。检查身体和认知功能可以帮助临床医生和研究人员更好地识别以不同速度老化的个人和群体。在未来的研究中,研究人员应该考虑识别不同的下降模式和速度的重要性,检查更多样化的测量类型之间的关系,并分析与年龄相关的下降发生的顺序。
On average, older people remember less and walk more slowly than do younger persons. Some researchers argue that this is due in part to a common biologic process underlying age-related declines in both physical and cognitive functioning. Only recently have longitudinal data become available for analyzing this claim. We conducted a systematic review of English-language research published between 2000 and 2011 to evaluate the relations between rates of change in physical and cognitive functioning in older cohorts. Physical functioning was assessed using objective measures: walking speed, grip strength, chair rise time, flamingo stand time, and summary measures of physical functioning. Cognition was measured using mental state examinations, fluid cognition, and diagnosis of impairment. Results depended on measurement type: Change in grip strength was more strongly correlated with mental state, while change in walking speed was more strongly correlated with change in fluid cognition. Examining physical and cognitive functioning can help clinicians and researchers to better identify individuals and groups that are aging differently and at different rates. In future research, investigators should consider the importance of identifying different patterns and rates of decline, examine relations between more diverse types of measures, and analyze the order in which age-related declines occur.
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发表时间: 2000-09-01
期刊: GERONTOLOGY
影响因子: 3.5
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