Oral Microbes, Biofilms and Their Role in Periodontal and Peri-Implant Diseases.
Oral Microbes, Biofilms and Their Role in Periodontal and Peri-Implant Diseases.
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DOI：
10.3390/ma11101802
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发表时间：
2018-09-22
期刊：
影响因子：
--
通讯作者：
Toma S
中科院分区：
文献类型：
--
作者：
Lasserre JF;Brecx MC;Toma S
尽管在过去的20年里，关于牙周和种植周疾病的病因发病机制有了许多发现，我们对微生物生物膜的理解也有了重大进展，但这些疾病的发病率仍在继续上升。这篇综述介绍了口腔健康和疾病的主要参与者和现象的总体概述。特别强调某些关键病原体在牙周炎和种植周炎中的作用。他们的能力带来失调与宿主和微生物生物膜的生活方式。最后，介绍了目前牙周炎和种植周炎的治疗原则，并指出了它们的局限性。这使我们认识到，必须制定和研究新的战略，以克服现有办法的缺点。
Despite many discoveries over the past 20 years regarding the etio-pathogenesis of periodontal and peri-implant diseases, as well as significant advances in our understanding of microbial biofilms, the incidence of these pathologies still continues to rise. This review presents a general overview of the main protagonists and phenomena involved in oral health and disease. A special emphasis on the role of certain keystone pathogens in periodontitis and peri-implantitis is underlined. Their capacity to bring a dysregulation of the homeostasis with their host and the microbial biofilm lifestyle are also discussed. Finally, the current treatment principles of periodontitis and peri-implantitis are presented and their limits exposed. This leads to realize that new strategies must be developed and studied to overcome the shortcomings of existing approaches.
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DOI：
10.1007/978-3-319-11038-7_5
发表时间：
2015-01-01
期刊：
BIOFILM-BASED HEALTHCARE-ASSOCIATED INFECTIONS, VOL I
影响因子：
--
作者：
Faveri, Marcelo;Figueiredo, Luciene Cristina;Feres, Magda
通讯作者：
Feres, Magda
影响因子：
7.6
作者：
Derks, J.;Schaller, D.;Berglundh, T.
通讯作者：
Berglundh, T.
影响因子：
6.7
作者：
BADERSTEN, A;NILVEUS, R;EGELBERG, J
通讯作者：
EGELBERG, J
影响因子：
3.6
作者：
Becker, Stephan T.;Beck-Broichsitter, Benedicta E.;Haesler, Robert
通讯作者：
Haesler, Robert
影响因子：
5.8
作者：
Duran-Pinedo AE;Frias-Lopez J
通讯作者：
Frias-Lopez J