Beyond microbial community composition: functional activities of the oral microbiome in health and disease.

Beyond microbial community composition: functional activities of the oral microbiome in health and disease.
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DOI:
10.1016/j.micinf.2015.03.014
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发表时间:
2015-07
影响因子:
5.8
通讯作者:
Frias-Lopez J
Frias-Lopez J
中科院分区:
医学3区
文献类型:
--
作者:
Duran-Pinedo AE;Frias-Lopez J

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口腔微生物组在宿主的健康状况中起着相关的作用,并且是各种口腔和非口腔疾病的关键因素。尽管我们对与不同健康状况相关的微生物组成变化的了解有所进展,但导致生态失调的口腔微生物组的功能方面在很大程度上仍然是未知的。在这篇综述中,我们讨论了在理解口腔微生物组在健康和疾病中的功能作用方面所取得的进展,以及新技术如何扩大我们对这一主题的认识。
The oral microbiome plays a relevant role in the health status of the host and is a key element in a variety of oral and non-oral diseases. Despite advances in our knowledge of changes in microbial composition associated with different health conditions the functional aspects of the oral microbiome that lead to dysbiosis remain for the most part unknown. In this review, we discuss the progress made towards understanding the functional role of the oral microbiome in health and disease and how novel technologies are expanding our knowledge on this subject.
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