Epidemiological Trends of Head and Neck Cancer in the United States: A SEER Population Study.
Epidemiological Trends of Head and Neck Cancer in the United States: A SEER Population Study.
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DOI：
10.1016/j.joms.2017.05.008
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发表时间：
2017-12
期刊：
影响因子：
--
通讯作者：
Urken ML
中科院分区：
文献类型：
--
作者：
Mourad M;Jetmore T;Jategaonkar AA;Moubayed S;Moshier E;Urken ML
这项研究代表了美国头颈癌 (HNC) 的最新流行病学趋势。它提供了关于口咽癌和与人乳头瘤病毒相关的癌症的重要讨论。目的是确定美国 HNC 的趋势（2002 年至 2012 年）。本研究是对美国国家癌症研究所提交的监测、流行病学和最终结果 (SEER) 的回顾性分析。使用 2014 年 11 月提交的 SEER 数据库和 SEER-18 数据文件，对 2002 年至 2012 年的数据进行了分析，以确定最新的流行病学趋势。所有亚型的 HNC 一起进行分析。喉癌单独进一步分析。对舌根部和扁桃体的口咽癌进行了独立分析，试图预测 HPV 相关癌症的趋势。从2002年到2012年，SEER数据库记录了149,301例HNC病例。 HNC 发病率每年下降 0.22% (P = .0549)，喉癌发病率每年下降 1.9% (P < .0001)。口咽癌（HPV 相关）的发病率每年增加 2.5% (P < .0001)。肯塔基州和康涅狄格州的 HNC 率显着上升，而加利福尼亚州则下降 (P < .05)。除乔治亚州、夏威夷州和密歇根州外，所有州的 HPV 相关癌症均显着增加 (P < .05)。加利福尼亚州、佐治亚州、新泽西州和新墨西哥州的喉癌发病率有所下降 (P < .05)。在美国，HNC 的总体发病率正在下降。与 HPV 相关的口咽癌的发病率不断增加。男性和女性之间的癌症发病率和变化率存在显着差异。此外，年轻群体的 HNC 总体下降幅度更大，而 50 岁以上患者的 HPV 相关癌症总体增加。
This study represents the most recent epidemiologic trends of head and neck cancer (HNC) in the United States. It provides an important discussion on oropharyngeal cancer and cancers related to the human papillomavirus. The objective was to identify trends in HNC (2002 to 2012) within the United States. This study is a retrospective analysis of the US National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) submission. Using the November 2014 submission of the SEER database and SEER-18 data files, data from 2002 to 2012 were analyzed to determine the most recent epidemiologic trends. HNCs of all subtypes were analyzed together. Laryngeal cancers were further analyzed separately. Oropharyngeal cancers of the base of tongue and tonsil were analyzed independently to attempt to trend HPV-related cancers. From 2002 to 2012, there were 149,301 cases of HNC recorded in the SEER database. The HNC rate decreased by 0.22% per year (P = .0549) and the rate of laryngeal cancer decreased by 1.9% per year (P < .0001). The rate of oropharyngeal (HPV-related) cancer increased by 2.5% per year (P < .0001). HNC rates increased significantly in Kentucky and Connecticut and decreased in California (P < .05). HPV-related cancers increased significantly in all states except Georgia, Hawaii, and Michigan (P < .05). Laryngeal cancer rates decreased in California, Georgia, New Jersey, and New Mexico (P < .05). The overall incidence of HNC is decreasing in the United States. There is an increasing incidence of HPV-related cancers of the oropharynx. Meaningful differences in cancer incidence and rate of change exist between men and women. Furthermore, younger groups have a greater decrease of overall HNC, with an overall increase in HPV-related cancer in patients older than 50 years.
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DOI：
10.1086/597755
发表时间：
2009-05-01
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
D'Souza G;Agrawal Y;Halpern J;Bodison S;Gillison ML
通讯作者：
Gillison ML
影响因子：
2.4
作者：
Everett, SA;Husten, CG;Crossett, L
通讯作者：
Crossett, L
影响因子：
45.3
作者：
Chaturvedi, Anil K.;Engels, Eric A.;Gillison, Maura L.
通讯作者：
Gillison, Maura L.
影响因子：
6.4
作者：
Blomberg, Maria;Nielsen, Ann;Kjaer, Susanne Kruger
通讯作者：
Kjaer, Susanne Kruger
影响因子：
6.4
作者：
Carvalho, AL;Nishimoto, IN;Kowalski, LP
通讯作者：
Kowalski, LP