Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort.
Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort.
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在一项大型横断面队列研究中，视网膜血管闭塞与认知性痴呆的关系。
DOI：
10.1016/j.ajo.2021.01.026
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发表时间：
2021-06
影响因子：
4.2
通讯作者：
Bakhoum, Mathieu F.
中科院分区：
文献类型：
--
作者：
Chan, Alison X.;Bakhoum, Christine Y.;Bangen, Katherine J.;Bakhoum, Mathieu F.
探讨认知性痴呆与视网膜血管阻塞之间的关系。一项回顾性横断面研究。单机构研究人群：我们审查了37，208名年龄超过65岁的个人的电子病历，这些人由眼科医生或验光师进行评估，并且在6年内也到我们的机构进行了医疗访问。根据国际疾病分类第10版（ICD-10）诊断代码确定有或无视网膜血管阻塞的个体。在调整了包括年龄、性别、中风、糖尿病和高血压在内的协变量后，我们使用多元逻辑回归分析分析了痴呆和视网膜血管阻塞之间的关系。与没有视网膜血管阻塞的受试者相比，视网膜血管阻塞的受试者痴呆的患病率更高（分别为6.7%和9.3%; P <0.001）。在调整了年龄或中风因素后，视网膜血管阻塞和痴呆之间没有明显的联系。视网膜血管阻塞的个体有较高的痴呆患病率。然而，这种关联是次要的共享的潜在风险因素在这个人群中，如老年和中风。
To examine the association between cognitive dementia and retinal vascular occlusions. A retrospective, cross-sectional study. Single-institution study population: we reviewed the electronic medical records of 37,208 individuals older than 65 years of age who were evaluated by an ophthalmologist or an optometrist and who also had a medical visit to our institution over a 6-year period. Individuals with and without retinal vascular occlusions were identified by International Classification of Diseases, version 10 (ICD-10) diagnostic codes. we analyzed the association between dementia and retinal vascular occlusions after adjusting for covariates which included age, sex, stroke, diabetes mellitus, and hypertension using multiple logistic regression analyses. Compared to subjects without retinal vascular occlusions, those with retinal vascular occlusions had a higher prevalence of dementia (6.7% vs. 9.3%, respectively; P < .001). After adjusting for either age or stroke, there were no significant associations between retinal vascular occlusions and dementia. Individuals with retinal vascular occlusions have a higher prevalence of dementia. However, this association is secondary to shared underlying risk factors in this population, such as older age and stroke.
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影响因子：
48
作者：
Kalaria, Raj N.;Maestre, Gladys E.;Arizaga, Raul;Friedland, Robert P.;Galasko, Doug;Hall, Kathleen;Luchsinger, Jose A.;Ogunniyi, Adesola;Perry, Elaine K.;Potocnik, Felix;Prince, Martin;Stewart, Robert;Wimo, Anders;Zhang, Zhen-Xin;Antuono, Piero
通讯作者：
Antuono, Piero
影响因子：
8.2
作者：
Rensma SP;van Sloten TT;Launer LJ;Stehouwer CDA
通讯作者：
Stehouwer CDA
影响因子：
4.9
作者：
Ponto, Katharina A.;Scharrer, Inge;Mirshahi, Alireza
通讯作者：
Mirshahi, Alireza
影响因子：
8.3
作者：
Schorr, Emily M.;Rossi, Kyle C.;Dhamoon, Mandip S.
通讯作者：
Dhamoon, Mandip S.
影响因子：
3.7
作者：
Zhang, Yi Stephanie;Zhou, Nina;Fawzi, Amani A.
通讯作者：
Fawzi, Amani A.