Pulse Transit Time Based Continuous Cuffless Blood Pressure Estimation: A New Extension and A Comprehensive Evaluation.
Pulse Transit Time Based Continuous Cuffless Blood Pressure Estimation: A New Extension and A Comprehensive Evaluation.
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DOI：
10.1038/s41598-017-11507-3
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发表时间：
2017-09-14
影响因子：
4.6
通讯作者：
Tsang HK
中科院分区：
文献类型：
--
作者：
Ding X;Yan BP;Zhang YT;Liu J;Zhao N;Tsang HK
无袖带技术能够以一种不显眼的方式连续测量血压，因此有可能彻底改变传统的基于袖带的方法。本研究通过引入光容积脉搏图（PPG）强度比（PIR）这一新的指标，扩展了基于脉冲传递时间（PTT）的无套管血压测量方法。综合评价了PTT和PIR模型的性能，并与仅基于PTT的6个模型进行了比较。验证分别在33名有高血压和无高血压的受试者中进行，分别在静止状态和在各种动作下引起血压变化，并在延长的校准间隔内进行。结果表明，与PTT模型相比，所提方法在静息状态和校正间隔超过24小时时对各被试组具有更好的精度。尽管所有方法在动态机动和过长校准间隔下的BP估计误差都显著增加，但在后一种情况下，所提方法仍优于比较方法。这些发现表明，除了PTT之外，额外的BP相关指标对于提高无套管血压测量的准确性具有附加价值。该研究还为未来无套管血压测量的研究提供了见解，用于跟踪动态血压变化和长时间的血压测量。
Cuffless technique enables continuous blood pressure (BP) measurement in an unobtrusive manner, and thus has the potential to revolutionize the conventional cuff-based approaches. This study extends the pulse transit time (PTT) based cuffless BP measurement method by introducing a new indicator – the photoplethysmogram (PPG) intensity ratio (PIR). The performance of the models with PTT and PIR was comprehensively evaluated in comparison with six models that are based on sole PTT. The validation conducted on 33 subjects with and without hypertension, at rest and under various maneuvers with induced BP changes, and over an extended calibration interval, respectively. The results showed that, comparing to the PTT models, the proposed methods achieved better accuracy on each subject group at rest state and over 24 hours calibration interval. Although the BP estimation errors under dynamic maneuvers and over extended calibration interval were significantly increased for all methods, the proposed methods still outperformed the compared methods in the latter situation. These findings suggest that additional BP-related indicator other than PTT has added value for improving the accuracy of cuffless BP measurement. This study also offers insights into future research in cuffless BP measurement for tracking dynamic BP changes and over extended periods of time.
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影响因子：
19
作者：
Luo, Ningqi;Dai, Wenxuan;Zhao, Ni
通讯作者：
Zhao, Ni
影响因子：
4.6
作者：
Martin SL;Carek AM;Kim CS;Ashouri H;Inan OT;Hahn JO;Mukkamala R
通讯作者：
Mukkamala R
影响因子：
4.3
作者：
Choi, Younhee;Zhang, Qiao;Ko, Seokbum
通讯作者：
Ko, Seokbum
影响因子：
3.2
作者：
Ding, Xiaorong;Zhang, Yuanting;Tsang, Hon Ki
通讯作者：
Tsang, Hon Ki
DOI：
10.1098/rspb.1922.0022
发表时间：
1922-04-01
期刊：
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-CONTAINING PAPERS OF A BIOLOGICAL CHARACTER
影响因子：
--
作者：
Bramwell, JC
通讯作者：
Bramwell, JC