Semantic Variant Primary Progressive Aphasia: Practical Recommendations for Treatment from 20 Years of Behavioural Research.
Semantic Variant Primary Progressive Aphasia: Practical Recommendations for Treatment from 20 Years of Behavioural Research.
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DOI：
10.3390/brainsci11121552
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发表时间：
2021-11-23
期刊：
影响因子：
3.3
通讯作者：
Taylor-Rubin C
中科院分区：
文献类型：
--
作者：
Suárez-González A;Savage SA;Bier N;Henry ML;Jokel R;Nickels L;Taylor-Rubin C
语义变异型原发性进行性失语症（svPPA）患者表现为语义知识的特征性进行性崩溃。目前还没有药物干预来治愈或减缓svPPA，但越来越多的报道了有前途的行为方法。本文概述了过去二十年的研究干预措施，以支持语言的人与svPPA，包括建议的临床实践和未来的研究的基础上，现有的最佳证据。我们以英语、西班牙语和法语提供通俗摘要，用于教育和传播目的。本文讨论了svPPA中右侧与左侧为主的萎缩的影响，命名疗法提供了最好的结果，以及如何利用保存的长期记忆系统。当前知识的维护和概括的语言治疗收益详细描述沿着与补偿方法和教育和支持小组计划的发展。它的结论是，有证据支持综合框架的治疗和护理的最佳实践svPPA。这种办法应结合联合收割机，采取康复干预措施，解决语言障碍问题，采取补偿性办法，支持日常生活活动，并在痴呆症的情况下提供教育和支持。
People with semantic variant primary progressive aphasia (svPPA) present with a characteristic progressive breakdown of semantic knowledge. There are currently no pharmacological interventions to cure or slow svPPA, but promising behavioural approaches are increasingly reported. This article offers an overview of the last two decades of research into interventions to support language in people with svPPA including recommendations for clinical practice and future research based on the best available evidence. We offer a lay summary in English, Spanish and French for education and dissemination purposes. This paper discusses the implications of right- versus left-predominant atrophy in svPPA, which naming therapies offer the best outcomes and how to capitalise on preserved long-term memory systems. Current knowledge regarding the maintenance and generalisation of language therapy gains is described in detail along with the development of compensatory approaches and educational and support group programmes. It is concluded that there is evidence to support an integrative framework of treatment and care as best practice for svPPA. Such an approach should combine rehabilitation interventions addressing the language impairment, compensatory approaches to support activities of daily living and provision of education and support within the context of dementia.
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DOI：
10.3109/17549507.2016.1151936
发表时间：
2016-01-01
影响因子：
1.8
作者：
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通讯作者：
Panegyres, Peter K.
影响因子：
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影响因子：
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作者：
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通讯作者：
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DOI：
10.1016/j.nicl.2018.05.035
发表时间：
2018
期刊：
NeuroImage. Clinical
影响因子：
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Guo Q