Value of SOFA, APACHE IV and SAPS II scoring systems in predicting short-term mortality in patients with acute myocarditis.

Value of SOFA, APACHE IV and SAPS II scoring systems in predicting short-term mortality in patients with acute myocarditis.
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SOFA、APACHE IV和SAPS II评分系统对急性心肌炎患者短期死亡率的预测价值

DOI:
10.18632/oncotarget.18634
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发表时间:
2017-09-08
期刊:
影响因子:
--
通讯作者:
Wang DW
Wang DW
中科院分区:
其他
文献类型:
--
作者:
Sun D;Ding H;Zhao C;Li Y;Wang J;Yan J;Wang DW

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急性心肌炎是一种罕见且可能危及生命的疾病。评分系统对于预测成人急性心肌炎患者的预后和评估治疗效果至关重要。本研究的目的是确定顺序器官衰竭评估(SOFA)、急性生理和慢性健康评估IV (APACHE IV)和第二简化急性生理评分(SAPS II)评分系统在预测这些患者短期死亡率方面的价值。我们回顾性分析了2005年4月至2016年8月期间305例急性心肌炎成年患者的数据。确定入院SOFA、APACHE IV和SAPS II评分值与短期死亡风险之间的关系。多因素Cox分析显示,SOFA、APACHE IV和SAPS II评分是急性心肌炎患者死亡的独立危险因素。对于每个评分系统,Kaplan-Meier分析显示,入院评分较高的患者的累积短期死亡率明显高于入院评分较低的患者。对于急性心肌炎患者的短期死亡率预测,SAPS II的准确性最高,其次是APACHE IV和SOFA评分。
Acute myocarditis is an uncommon and potentially life-threatening disease. Scoring systems are essential for predicting outcome and evaluating the therapy effect of adult patients with acute myocarditis. The aim of this study was to determine the value of the Sequential Organ Failure Assessment (SOFA), Acute Physiology and Chronic Health Evaluation IV (APACHE IV) and second Simplified Acute Physiology Score (SAPS II) scoring systems in predicting short-term mortality of these patients. We retrospectively analyzed data from 305 adult patients suffering from acute myocarditis between April 2005 and August 2016. The association between the value of admission SOFA, APACHE IV and SAPS II scores and risk of short-term mortality was determined. Multivariate Cox analysis showed that SOFA, APACHE IV and SAPS II scores were independent risk factors of death in patients with acute myocarditis. For each scoring system, Kaplan–Meier analysis showed that the cumulative short-term mortality was significantly higher in patients with higher admission scores compared with those with lower admission scores. For the prediction of short-term mortality in a patient with acute myocarditis, SAPS II had the highest accuracy followed by the APACHE IV and SOFA scores.
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