The prevalence and clinical significance of intracranial vertebral artery terminated in posterior inferior cerebellar artery: A multicenter hospital-based study in China.
The prevalence and clinical significance of intracranial vertebral artery terminated in posterior inferior cerebellar artery: A multicenter hospital-based study in China.
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颅内椎动脉终止于小脑后下动脉的患病率及临床意义：一项基于中国医院的多中心研究
DOI：
10.3389/fneur.2022.1026614
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发表时间：
2022
影响因子：
3.4
通讯作者：
Jiang, Yongjun
中科院分区：
文献类型：
--
作者：
Zhu, Juehua;Huang, Ruiyun;Ye, Kaiwen;Chen, Hongbing;Dai, Zheng;Jiang, Yongjun
关键词：
颅内椎动脉终止于小脑后下动脉（PICA-VA）是小脑后下动脉最常见的变异，但其发生率和临床意义尚不清楚。在本研究中，我们的目的是调查PICA-VA的患病率和临床意义。这是一项基于医院的多中心横断面研究。患者在卒中发作1周内入组接受脑MRI和MRA。记录临床特征。PICA-VA被称为不与基底动脉连通但终止于同侧PICA的椎动脉。我们观察PICA-VA的患病率，并确定PICA-VA与椎基底动脉卒中的关系。从2015年8月1日至2017年5月31日，本研究共入组了2，528例患者。PICA-VA变异95例（3.76%，95/2,528），其中51例（53.7%）位于右侧。PICA-VA患者椎基底动脉卒中的患病率显著高于无PICA-VA患者（40.2%，37/92 vs. 17.1%，417/2，436，p < 0.01）。在校正颅内出血、糖尿病、体重指数和甘油三酯史后，PICA-VA是椎基底动脉卒中的独立风险。目前的研究表明，3.76%的急性脑卒中患者有PICA-VA，这独立地增加了急性椎基底动脉卒中的风险。
Intracranial vertebral artery terminated in the posterior inferior cerebellar artery (PICA-VA) is the most popular variant of the posterior inferior cerebellar artery, while its prevalence and clinical significance remained unclear. In the present study, we aimed to investigate the prevalence and clinical significance of PICA-VA. This was a multicenter hospital-based cross-sectional study. Patients were enrolled for cerebral MRI and MRA within 1 week of stroke onset. Clinical characteristics were recorded. PICA-VA is termed as a vertebral artery that does not communicate with the basilar artery but terminates in an ipsilateral PICA. We observed the prevalence of PICA-VA and identified a relationship between PICA-VA and vertebrobasilar stroke. From 1 August 2015 to 31 May 2017, a total of 2,528 patients were enrolled in the present study. Among them, 95 patients (3.76%, 95/2,528) had the variation of PICA-VA, 51 of which (53.7%) were located on the right side. The prevalence of vertebrobasilar stroke was considerably higher in patients with PICA-VA than those without (40.2%, 37/92 vs. 17.1%, 417/2,436, p < 0.01). PICA-VA was an independent risk for vertebrobasilar stroke after being adjusted for a history of intracranial hemorrhage, diabetes, body mass index, and triglyceride. The present study showed that 3.76% of patients with acute stroke had PICA-VA, which independently increased the risk of acute vertebrobasilar stroke.
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影响因子：
2.6
作者：
Huang, Jiehong;Qiu, Zhihua;Jiang, Yongjun
通讯作者：
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影响因子：
2.6
作者：
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Xu WH
椎动脉支架置入术后二元再狭窄的发生率、风险和治疗
影响因子：
2.3
作者：
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影响因子：
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作者：
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通讯作者：
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