Developmental pathways of adolescent cannabis use: Risk factors, outcomes and sex-specific differences.

Developmental pathways of adolescent cannabis use: Risk factors, outcomes and sex-specific differences.
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DOI:
10.1080/10826084.2018.1517177
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发表时间:
2019
影响因子:
2
通讯作者:
Gonzalez R
Gonzalez R
中科院分区:
医学4区
文献类型:
--
作者:
Hawes SW;Trucco EM;Duperrouzel JC;Coxe S;Gonzalez R

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Characterizing patterns of adolescent cannabis use (CU), as well as risk factors and outcomes uniquely associated with these pathways is essential for informing treatment and prevention efforts. Yet, few studies have examined these issues among youth at-risk of engaging in problematic cannabis use. Further, research accounting for use of other substances or sex differences in patterns of CU remains exceedingly sparse. Trajectory-based modeling was used to identify underlying CU pathways among a predominantly Hispanic (90%) sample of at-risk youth (n=401; 46% female) across adolescence (ages~14–18), controlling for baseline substance use and participant demographics. Adolescent psychopathology (i.e., conduct disorder, ADHD, anxiety, depression) was examined as a predictor and outcome of CU. Three trajectories of adolescent CU were identified, with most youth (74%) engaging in relatively ‘low’ levels of use, followed by approximately 12% exhibiting an early-initiating ‘chronic’ course, and 14% ‘escalating’ in use. Although boys and girls both experienced increased levels of CU across adolescence, boys were more likely to exhibit escalating and chronic patterns of use. Findings revealed unique associations between adolescent CU pathways and facets of psychopathlogy; most notably, the relatively robust and bidirectional association between CU trajectories and conduct problem symptoms. Specific facets of psychopathology may confer unique associations with CU across development, including the initiation and exacerbation of CU during adolescence.
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