Performance of young adult cannabis users on neurocognitive measures of impulsive behavior and their relationship to symptoms of cannabis use disorders.
Performance of young adult cannabis users on neurocognitive measures of impulsive behavior and their relationship to symptoms of cannabis use disorders.
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DOI：
10.1080/13803395.2012.703642
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发表时间：
2012
影响因子：
2.2
通讯作者：
Diviak KR
中科院分区：
文献类型：
--
作者：
Gonzalez R;Schuster RM;Mermelstein RJ;Vassileva J;Martin EM;Diviak KR
最近的研究表明，禁欲的大麻使用者在冲动行为的神经认知实验室任务方面表现出缺陷。但结果好坏参半，对非寻求治疗的年轻成年大麻使用者的表现知之甚少。重要的是，冲动行为和大麻成瘾症状之间的关系仍然相对未被探索。我们比较了年轻的成年人目前的大麻用户（CU，n = 65）和非使用控制（NU，n = 65）的冲动行为的几个实验室措施，以及对情节记忆的措施通常受到大麻使用的影响。CU组在霍普金斯言语学习测验-修订的完全立即回忆和延迟回忆中的表现比NU组差。在冲动行为的测量上没有观察到显著差异（即，爱荷华州赌博任务[IGT]，去-停任务，货币选择问卷，气球抵押风险任务）。我们研究了CU组中神经认知表现与大麻使用障碍症状（DSM-IV CUD）症状之间的关系，结果显示IGT表现较差与DSM-IV CUD症状更多相关。我们的研究结果显示，年轻的成年大麻使用者相对于健康对照组的记忆表现较差，但在冲动行为的测量上没有差异。然而，在特定类型的冲动行为（即，决策能力较差）与更多的大麻使用障碍症状有关。这些结果提供了初步证据，表明决策缺陷可能与大麻使用所经历的问题更密切相关，而不仅仅是大麻使用本身的后果。
Recent studies suggest that abstinent cannabis users show deficits on neurocognitive laboratory tasks of impulsive behavior. But results are mixed and less is known on the performance of non-treatment seeking, young adult cannabis users. Importantly, relationships between performance on measures of impulsive behavior and symptoms of cannabis addiction remain relatively unexplored. We compared young adult current cannabis users (CU, n = 65) and non-using controls (NU, n = 65) on several laboratory measures of impulsive behavior, as well as on a measure of episodic memory commonly impacted by cannabis use. The CU group performed more poorly than the NU group on the Hopkins Verbal Learning Test-Revised Total Immediate Recall and Delayed Recall. No significant differences were observed on the measures of impulsive behavior (i.e., Iowa Gambling Task [IGT], Go-Stop Task, Monetary Choice Questionnaire, Balloon Analogue Risk Task). We examined relationships between neurocognitive performance and symptoms of cannabis use disorder symptoms (DSM-IV CUD) among the CU group, which revealed that poorer IGT performance was associated with more symptoms of DSM-IV CUD. Our results show poorer memory performance among young adult cannabis users relative to healthy controls, but no differences on measures of impulsive behavior. However, performance on a specific type of impulsive behavior (i.e., poorer decision-making) was associated with more cannabis use disorder symptoms. These results provide preliminary evidence to suggest that decision-making deficits may be more strongly associated with problems experienced from cannabis use, rather than solely being a consequence of cannabis use, per se.
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影响因子：
5.5
作者：
Crean RD;Crane NA;Mason BJ
通讯作者：
Mason BJ
影响因子：
1.1
作者：
Dougherty DM;Mathias CW;Marsh-Richard DM;Furr RM;Nouvion SO;Dawes MA
通讯作者：
Dawes MA
影响因子：
4.2
作者：
Fernie, Gordon;Cole, Jon C.;Field, Matt
通讯作者：
Field, Matt
影响因子：
4.2
作者：
Dougherty, Donald M.;Marsh-Richard, Dawn M.;Mathias, Charles W.
通讯作者：
Mathias, Charles W.
影响因子：
2.3
作者：
Anthony, James C.;Warner, Lynn A.;Kessler, Ronald C.
通讯作者：
Kessler, Ronald C.