Pragmatic language and school related linguistic abilities in siblings of children with autism.
Pragmatic language and school related linguistic abilities in siblings of children with autism.
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DOI：
10.1007/s10803-010-1096-6
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发表时间：
2011-06
影响因子：
3.9
通讯作者：
Sigman, Marian
中科院分区：
文献类型：
--
作者：
Ben-Yizhak, Noa;Yirmiya, Nurit;Seidman, Ifat;Alon, Raaya;Lord, Catherine;Sigman, Marian
孤独症谱系障碍先证者的遗传变异具有更高的发展广泛孤独症表型（BAP）的风险。我们比较了语言能力（即，语用语言，学校成绩，和底层阅读过程）的35个学龄兄弟姐妹的自闭症儿童（SIBS-A）的42个兄弟姐妹的儿童与典型的发展。结果表明，低语用能力的一个亚组的SIBS-A确定与BAP相关的困难（SIBS-A-BAP），而学业成绩和阅读过程是完整的。此外，在SIBS-A-BAP中，自闭症诊断观察表的严重程度评分与全面和言语智商评分之间存在显着的负相关。这些结果进行了讨论的背景下的发展轨迹的SIBS-A和BAP。
Siblings of probands with autism spectrum disorders are at higher risk for developing the broad autism phenotype (BAP). We compared the linguistic abilities (i.e., pragmatic language, school achievements, and underling reading processes) of 35 school-age siblings of children with autism (SIBS-A) to those of 42 siblings of children with typical development. Results indicated lower pragmatic abilities in a subgroup of SIBS-A identified with BAP related difficulties (SIBS-A-BAP) whereas school achievements and reading processes were intact. Furthermore, among SIBS-A-BAP, significant negative correlations emerged between the severity scores on the Autism Diagnostic Observation Schedule and full and verbal IQ scores. These results are discussed in the context of the developmental trajectories of SIBS-A and in relation to the BAP.
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影响因子：
3.9
作者：
Gotham, Katherine;Pickles, Andrew;Lord, Catherine
通讯作者：
Lord, Catherine
自闭症诊断观察表： 提高诊断有效性的修订算法
影响因子：
3.9
作者：
Gotham, Katherine;Risi, Susan;Lord, Catherine
通讯作者：
Lord, Catherine
影响因子：
168.9
作者：
Levy, Susan E.;Mandell, David S.;Schultz, Robert T.
通讯作者：
Schultz, Robert T.
DOI：
10.1111/j.1469-7610.2006.01531.x
发表时间：
2006-06-01
影响因子：
7.6
作者：
Landa, Rebecca;Garrett-Mayer, Elizabeth
通讯作者：
Garrett-Mayer, Elizabeth
影响因子：
3.9
作者：
Gamliel, Ifat;Yirmiya, Nurit;Sigman, Marian
通讯作者：
Sigman, Marian