Association of Markers of Inflammation with Sleep and Physical Activity Among People Living with HIV or AIDS.
Association of Markers of Inflammation with Sleep and Physical Activity Among People Living with HIV or AIDS.
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DOI：
10.1007/s10461-014-0949-y
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发表时间：
2015-06
影响因子：
4.4
通讯作者：
Hand, Gregory A.
中科院分区：
文献类型：
--
作者：
Wirth, Michael D.;Jaggers, Jason R.;Dudgeon, Wesley D.;Hebert, James R.;Youngstedt, Shawn D.;Blair, Steven N.;Hand, Gregory A.
本研究调查了艾滋病毒感染者（PLWH）的睡眠和中等强度体力活动（MVPA）时间与C反应蛋白（CRP）和白细胞介素（IL）-6的关系。横断面分析（n=45）集中在炎症结局的相关性（即，CRP和IL-6）与活动记录仪衍生的睡眠持续时间、潜伏期和效率;就寝时间;觉醒时间;和入睡后觉醒;以及MVPA。根据一般线性模型计算CRP和IL-6的睡眠水平和MVPA的最小二乘均值。低于睡眠时间中位数、高于就寝时间中位数和低于MVPA分钟中位数的个体具有较高的CRP或IL-6水平。一般来说，MVPA低和睡眠质量差的人的炎症水平高于MVPA高和睡眠质量好的人。了解多种生活方式/行为因素对炎症的综合影响可以为减少炎症的干预策略提供信息，从而减少慢性疾病的风险。
This study examined associations of sleep and minutes spent in moderate-vigorous physical activity (MVPA) with C-reactive protein (CRP) and interleukin (IL)-6 among persons living with HIV (PLWH). Cross-sectional analyses (n=45) focused on associations of inflammatory outcomes (i.e., CRP and IL-6) with actigraph-derived sleep duration, latency, and efficiency; bedtime; wake time; and wake-after-sleep-onset; as well as MVPA. Least square means for CRP and IL-6 by levels of sleep and MVPA were computed from general linear models. Individuals below the median of sleep duration, above the median for bedtime, and below the median of MVPA minutes had higher CRP or IL-6 levels. Generally, individuals with both low MVPA and poor sleep characteristics had higher inflammation levels than those with more MVPA and better sleep. Understanding the combined impact of multiple lifestyle/behavioral factors on inflammation could inform intervention strategies to reduce inflammation and therefore, chronic disease risk.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
3.8
作者：
Chennaoui, M.;Sauvet, F.;Gomez-Merino, D.
通讯作者：
Gomez-Merino, D.
DOI：
10.1080/09540120701796900
发表时间：
2008-10-01
影响因子：
1.7
作者：
Hand, Gregory A.;Phillips, Kenneth D.;Burgess, Stephanie E.
通讯作者：
Burgess, Stephanie E.
影响因子：
4.7
作者：
Cruess, DG;Antoni, MH;Schneiderman, N
通讯作者：
Schneiderman, N
影响因子：
1.1
作者：
Kline CE;Zielinski MR;Devlin TM;Kripke DF;Bogan RK;Youngstedt SD
通讯作者：
Youngstedt SD