Smoking cessation in pregnancy and the risk of child behavioural problems: a longitudinal prospective cohort study
Smoking cessation in pregnancy and the risk of child behavioural problems: a longitudinal prospective cohort study
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怀孕期间戒烟和儿童行为问题的风险：一项纵向前瞻性队列研究
DOI：
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发表时间：
2009
影响因子：
6.3
通讯作者：
J. Newnham
中科院分区：
文献类型：
--
作者：
M. Robinson;Neil J. McLean;W. Oddy;E. Mattes;M. Bulsara;Jianghong Li;S. Zubrick;F. Stanley;J. Newnham
背景本研究的目的是在一个大型前瞻性怀孕队列中，与在怀孕前18周内戒烟的母亲和从不吸烟的母亲进行比较，研究怀孕期间吸烟对儿童和青少年行为发育的影响。 西澳大利亚妊娠队列研究（Raine）提供了2900例妊娠的综合数据。在妊娠18周时评估吸烟情况，并在1、2、3、5、8、10和14岁时对儿童进行随访。 儿童行为检查表（CBCL）被用来衡量问题儿童的行为与连续的z分数和临床分界点，在年龄2，5，8，10和14岁。 潜在的混杂因素包括母亲和家庭的社会人口学特征和酒精暴露。结果在调整混杂因素后，轻度吸烟者在妊娠18周前戒烟的儿童的CBCL总z评分显著低于从不吸烟的妇女的儿童，重度吸烟者戒烟和继续吸烟的儿童，表明行为更好。 母亲在怀孕期间吸烟导致更高的CBCL总，内化和外化分数和更高的风险，有临床意义的行为问题的儿童从2岁到14岁。结论母亲在怀孕期间决定不戒烟或无法戒烟似乎是儿童不良行为结果的一个特别强的标志。有必要更好地了解与怀孕期间戒烟的决定和能力相关的社会心理特征。
Background The aim of this study was to examine the influence of smoking in pregnancy on child and adolescent behavioural development, in comparison with mothers who ceased smoking in the first 18 weeks of pregnancy and with those who never smoked, in a large prospective pregnancy cohort. Methods The Western Australian Pregnancy Cohort (Raine) Study provided comprehensive data from 2900 pregnancies. Smoking was assessed at 18 weeks gestation, and children were followed up at ages 1, 2, 3, 5, 8, 10 and 14 years. The Child Behaviour Checklist (CBCL) was used to measure problem child behaviour with continuous z-scores and clinical cut points at ages 2, 5, 8, 10 and 14 years. Potential confounders included maternal and family sociodemographic characteristics and alcohol exposure. Results After adjusting for confounders, children of light smokers who quit smoking by 18 weeks gestation had significantly lower CBCL total z-scores, indicative of better behaviour, than children of women who never smoked, children of heavy smokers who quit and continuing smokers. Maternal smoking during pregnancy resulted in higher CBCL total, internalising and externalising scores and a higher risk of clinically meaningful behaviour problems in children from ages 2 to 14. Conclusion The maternal decision not to quit smoking, or the inability to quit smoking, during pregnancy appears to be a particularly strong marker for poor behavioural outcomes in children. There is a need for a greater understanding of the psychosocial characteristics associated with the decision and ability to quit smoking in pregnancy.
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DOI：
10.1097/00004583-199907000-00020
发表时间：
1999-07-01
影响因子：
13.3
作者：
Weissman, MM;Warner, V;Kandel, DB
通讯作者：
Kandel, DB
戒烟计划中的自我效能和复发。
影响因子：
5.9
作者：
Condiotte,MM;Lichtenstein,E
通讯作者：
Lichtenstein,E
影响因子：
120.7
作者：
Lasser, K;Boyd, JW;Bor, DH
通讯作者：
Bor, DH
影响因子：
5.4
作者：
Wakschlag, LS;Pickett, KE;Leventhal, BL
通讯作者：
Leventhal, BL