Role of dietary patterns and acculturation in cancer risk and mortality among postmenopausal Hispanic women: results from the Women's Health Initiative (WHI).
Role of dietary patterns and acculturation in cancer risk and mortality among postmenopausal Hispanic women: results from the Women's Health Initiative (WHI).
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DOI：
10.1007/s10389-020-01342-8
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发表时间：
2022-04
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影响因子：
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研究饮食模式与总体癌症和肥胖相关癌症风险之间的关系。此外，要检查是否涵化修改这种关系。根据食物频率问卷估计参加妇女健康倡议的绝经后西班牙裔妇女（N= 5，482）的饮食摄入量，并用于计算饮食模式评分;健康饮食指数-2015（HEI-2015）、墨西哥饮食（MexD）评分、替代地中海饮食评分（aMED）和能量调整饮食炎症指数（E-DII™）。使用考克斯比例风险回归模型评估相关性。在平均12年的随访中，诊断出631种癌症和396种肥胖相关癌症。在饮食评分中，与癌症风险或死亡率没有显着相关性。趋势分析表明，与最高MexD评分相关的总癌症风险可能较低（HR 0.68，95% CI 0.45-1.04，P趋势=0.03），与MexD最高评分类别相关的肥胖相关癌症死亡率风险较低（HR 0.65，95% CI 0.37-1.16，P趋势=0.02）和aMED（HR 0.87，95% CI 0.45-1.67，P趋势=0.04）。进一步的分析表明，与文化适应程度较高的西班牙裔女性相比，文化适应程度较低且MexD评分较高的女性患任何癌症的风险降低56%（HR 0.44，95% CI 0.22-0.88，P趋势=0.03），癌症死亡率风险降低83%（HR 0.17，95% CI 0.04-0.76，P趋势=0.01）。饮食模式与绝经后西班牙裔妇女的癌症风险和死亡率无关。文化适应程度较低，喜欢说西班牙语的人，报告说消费更传统的墨西哥饮食可能会降低患癌症和癌症死亡率的风险。
To investigate the association between dietary patterns and total and obesity-related cancers risk. Additionally, to examine if acculturation modifies this relationship. Dietary intake of postmenopausal Hispanic women (N=5,482) enrolled in the Women’s Health Initiative was estimated from a Food Frequency Questionnaire and used to calculate dietary pattern scores; Healthy Eating Index-2015 (HEI-2015), Mexican Diet (MexD) score, alternate Mediterranean Diet Score (aMED), and the energy adjusted-Dietary Inflammatory Index (E-DII™). Associations were evaluated using Cox proportional hazards regression models. 631 cancers and 396 obesity-related cancers were diagnosed over a mean-follow up of 12 years. Across dietary scores, there were no significant associations with cancer risk or mortality. Trend analysis suggest a potentially lower risk for total cancer related to the highest MexD score (HR 0.68, 95% CI 0.45–1.04, P-trend=0.03), and lower risk for obesity-related cancer mortality related to the highest score category for MexD (HR 0.65, 95% CI 0.37–1.16, P-trend=0.02), and aMED (HR 0.87, 95% CI 0.45–1.67, P-trend=0.04). Further analysis suggests less acculturated women with higher MexD scores had 56% lower risk for any cancer (HR 0.44, 95% CI 0.22–0.88, P-trend=0.03) and 83% lower risk for cancer mortality (HR 0.17, 95% CI 0.04–0.76, P-trend=0.01) compared to more acculturated Hispanic women. Dietary patterns were not associated with cancer risk and mortality in postmenopausal Hispanic women. Less-acculturated, Spanish-preferred speakers, who reported consuming a more traditional Mexican diet may experience a lower risk for cancer and cancer mortality.
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影响因子：
29.4
作者：
Park SY;Boushey CJ;Wilkens LR;Haiman CA;Le Marchand L
通讯作者：
Le Marchand L
影响因子：
--
作者：
Arcidiacono B;Iiritano S;Nocera A;Possidente K;Nevolo MT;Ventura V;Foti D;Chiefari E;Brunetti A
通讯作者：
Brunetti A
影响因子：
7.1
作者：
Harmon, Brook E.;Boushey, Carol J.;Kolonel, Laurence N.
通讯作者：
Kolonel, Laurence N.
影响因子：
4.2
作者：
Harmon, Brook E.;Wirth, Michael D.;Hebert, James R.
通讯作者：
Hebert, James R.
影响因子：
4.2
作者：
Fung, TT;Hu, FB;Holmes, MD
通讯作者：
Holmes, MD