Mechanisms of obesity-induced gastrointestinal neoplasia.
Mechanisms of obesity-induced gastrointestinal neoplasia.
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DOI:
10.1053/j.gastro.2013.11.051
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发表时间:
2014-02
期刊:
影响因子:
29.4
通讯作者:
Holt PR
中科院分区:
文献类型:
--
作者:
Alemán JO;Eusebi LH;Ricciardiello L;Patidar K;Sanyal AJ;Holt PR
Obesity is among the fastest growing diseases worldwide; treatment is inadequate and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. We review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.
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