Cellular-level surgery using nano robots.
Cellular-level surgery using nano robots.
复制标题
DOI:
10.1177/2211068212460665
复制
发表时间:
2012-12
期刊:
影响因子:
--
通讯作者:
Lai KW
中科院分区:
文献类型:
--
作者:
Song B;Yang R;Xi N;Patterson KC;Qu C;Lai KW
The atomic force microscope (AFM) is a popular instrument for studying the nano world. AFM is naturally suitable for imaging living samples and measuring mechanical properties. In this article, we propose a new concept of an AFM-based nano robot that can be applied for cellular-level surgery on living samples. The nano robot has multiple functions of imaging, manipulation, characterizing mechanical properties, and tracking. In addition, the technique of tip functionalization allows the nano robot the ability for precisely delivering a drug locally. Therefore, the nano robot can be used for conducting complicated nano surgery on living samples, such as cells and bacteria. Moreover, to provide a user-friendly interface, the software in this nano robot provides a “videolized” visual feedback for monitoring the dynamic changes on the sample surface. Both the operation of nano surgery and observation of the surgery results can be simultaneously achieved. This nano robot can be easily integrated with extra modules that have the potential applications of characterizing other properties of samples such as local conductance and capacitance.
登录
查看更多内容
影响因子:
3.9
作者:
Fung CK;Xi N;Yang R;Seiffert-Sinha K;Lai KW;Sinha AA
通讯作者:
Sinha AA
DOI:
10.1073/pnas.0403538101
发表时间:
2004-08-24
影响因子:
11.1
作者:
Stroh, C;Wang, H;Hinterdorfer, P
通讯作者:
Hinterdorfer, P
影响因子:
6.6
作者:
Grudinkin, Pavel S.;Zenin, Valery V.;Nikolsky, Nikolay N.
通讯作者:
Nikolsky, Nikolay N.
影响因子:
1.6
作者:
Xi, Ning;Fung, Carmen Kar Man;Sinha, Animesh A.
通讯作者:
Sinha, Animesh A.
DOI:
10.1016/j.nano.2009.05.008
发表时间:
2010-02-01
影响因子:
5.4
作者:
Fung, Carmen Kar Man;Seiffert-Sinha, Kristina;Sinha, Animesh A.
通讯作者:
Sinha, Animesh A.