Bladder cancer detection and monitoring: assessment of urine- and blood-based marker tests.

Bladder cancer detection and monitoring: assessment of urine- and blood-based marker tests.
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DOI:
10.1007/s40291-013-0023-x
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发表时间:
2013-04
影响因子:
4
通讯作者:
Urquidi, Virginia
Urquidi, Virginia
中科院分区:
医学3区
文献类型:
--
作者:
Goodison, Steve;Rosser, Charles J.;Urquidi, Virginia

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膀胱癌是世界上最常见的癌症之一,但如果及早发现,这种疾病的治疗和管理可以非常成功。能够在早期准确诊断膀胱癌的分子检测方法的发展将是一个重大的进步。理想情况下,这种分子检测方法将适用于非侵入性获取的体液,不仅用于诊断,还用于监测疾病复发和治疗反应。在这篇文章中,我们评估了当前膀胱癌诊断方法的性能,并讨论了一些新出现的生物标志物,这些生物标志物可以被开发来增强当前的膀胱癌检测策略。
Bladder cancer is one of the most prevalent cancers worldwide, but the treatment and management of this disease can be very successful if the disease is detected early. The development of molecular assays that could diagnose bladder cancer accurately, and at an early stage, would be a significant advance. Ideally, such molecular assays would be applicable to non-invasively obtained body fluids, and be designed not only for diagnosis but also for monitoring disease recurrence and response to treatment. In this article, we assess the performance of current diagnostic assays for bladder cancer and discuss some of the emerging biomarkers that could be developed to augment current bladder cancer detection strategies.
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