Management of hepatocellular carcinoma: an overview of major findings from meta-analyses.

Management of hepatocellular carcinoma: an overview of major findings from meta-analyses.
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DOI:
10.18632/oncotarget.9157
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发表时间:
2016-06-07
期刊:
影响因子:
--
通讯作者:
Han G
Han G
中科院分区:
其他
文献类型:
--
作者:
Qi X;Zhao Y;Li H;Guo X;Han G

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本文旨在系统地回顾荟萃分析比较肝细胞癌(HCC)不同治疗方案的主要结果。通过PubMed、EMBASE和科克伦图书馆数据库共检索了153篇相关论文。根据主要治疗方式(即,肝移植、手术切除、射频消融、经动脉栓塞或化疗栓塞、索拉非尼等)。总结了主要结局数据,如总生存期、无疾病生存期或无复发生存期、无进展生存期和安全性。并对肝癌的治疗提出了建议和不确定性。
This paper aims to systematically review the major findings from meta-analyses comparing different treatment options for hepatocellular carcinoma (HCC). A total of 153 relevant papers were searched via the PubMed, EMBASE, and Cochrane library databases. They were classified according to the mainstay treatment modalities (i.e., liver transplantation, surgical resection, radiofrequency ablation, transarterial embolization or chemoembolization, sorafenib, and others). The primary outcome data, such as overall survival, diseases-free survival or recurrence-free survival, progression-free survival, and safety, were summarized. The recommendations and uncertainties regarding the treatment of HCC were also proposed.
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