Bidirectional associations of accelerometer measured sedentary behavior and physical activity with knee pain, stiffness, and physical function: The CARDIA study.
Bidirectional associations of accelerometer measured sedentary behavior and physical activity with knee pain, stiffness, and physical function: The CARDIA study.
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DOI：
10.1016/j.pmedr.2021.101348
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发表时间：
2021-06
影响因子：
2.8
通讯作者：
Jacobs DR Jr
中科院分区：
文献类型：
--
作者：
Whitaker KM;Pettee Gabriel K;Laddu D;White DK;Sidney S;Sternfeld B;Lewis CE;Jacobs DR Jr
目的是检查加速度计估计的久坐时间和身体活动与报告的膝关节症状的双向关联。参与者为来自CARDIA的2，034名成年人（平均年龄45.3 ± 3.6岁，58.7%为女性）。logistic回归和线性混合回归模型的广义估计方程检查了基线（2005-06年）加速计估计的久坐时间、轻强度体力活动（LPA）和中度至剧烈强度体力活动（MVPA）与膝关节不适、疼痛、僵硬、5年和10年随访检查时的身体功能（是/否和来自简短WOMAC功能量表的连续评分）。线性回归模型检查了5年随访时膝关节症状与10年随访时加速度计估计值之间的相关性。调整模型的混杂因素;在敏感性分析中排除合并症的个体。基线时久坐时间增加30分钟/天与5年和10年随访时膝关节症状发生率降低相关（OR：0.95，95% CI范围：0.92-0.98），而LPA和MVPA与膝关节症状的几率更大相关（LPA OR范围：1.04-1.05，95%CI范围：1.01-1.09; MVPA OR范围：1.17-1.19，95%CI范围：1.06-1.32）。与未报告症状的患者相比，5年随访时报告膝关节症状的患者久坐时间减少13.52-17.51分钟/天（95% CI范围：−29.90，−0.56），10年随访时LPA增加14.58-17.51分钟/天（95% CI范围：2.48，29.38）。当排除合并症的个体时，许多相关性不再具有统计学显著性。研究结果支持一个双向关联的加速度计估计久坐不动的时间和身体活动与膝盖症状在中年。
The objective was to examine bidirectional associations of accelerometer estimated sedentary time and physical activity with reported knee symptoms. Participants were 2,034 adults (mean age 45.3 ± 3.6 years, 58.7% female) from CARDIA. Generalized estimating equations for logistic regression and linear mixed regression models examined associations of accelerometer estimated sedentary time, light-intensity physical activity (LPA), and moderate-to-vigorous intensity physical activity (MVPA) at baseline (2005–06) with knee discomfort, pain, stiffness, and physical function (yes/no and continuous scores from short-form WOMAC function scale) at the 5- and 10-year follow-up exams. Linear regression models examined associations between knee symptoms at the 5-year follow-up with accelerometer estimates at the 10-year follow-up. Models were adjusted for confounders; individuals with comorbidities were excluded in sensitivity analyses. A 30 min/day increment in sedentary time at baseline was associated with lower odds of knee symptoms at the 5- and 10-year follow-up (OR: 0.95, 95% CI range: 0.92–0.98), while LPA and MVPA were associated with greater odds of knee symptoms (LPA OR range: 1.04–1.05, 95% CI range: 1.01–1.09; MVPA OR range: 1.17–1.19, 95% CI range: 1.06–1.32). Report of knee symptoms at the 5-year follow-up was associated with 13.52–17.51 (95% CI range: −29.90, −0.56) fewer minutes/day of sedentary time and 14.58–17.51 (95% CI range: 2.48, 29.38) more minutes/day of LPA at the 10-year follow-up, compared to those reporting no symptoms. Many associations were no longer statistically significant when excluding individuals with comorbidities. Findings support a bidirectional association of accelerometer estimated sedentary time and physical activity with knee symptoms across midlife.
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DOI：
10.1155/2016/1813979
发表时间：
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期刊：
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影响因子：
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2003-07-01
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The American journal of medicine
影响因子：
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