Genetic homogeneity of goat malaria parasites in Asia and Africa suggests their expansion with domestic goat host.
Genetic homogeneity of goat malaria parasites in Asia and Africa suggests their expansion with domestic goat host.
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DOI：
10.1038/s41598-018-24048-0
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发表时间：
2018-04-11
影响因子：
4.6
通讯作者：
Kaneko O
中科院分区：
文献类型：
--
作者：
Kaewthamasorn M;Takeda M;Saiwichai T;Gitaka JN;Tiawsirisup S;Imasato Y;Mossaad E;Sarani A;Kaewlamun W;Channumsin M;Chaiworakul S;Katepongpun W;Teeveerapunya S;Panthong J;Mureithi DK;Bawm S;Htun LL;Win MM;Ismail AA;Ibrahim AM;Suganuma K;Hakimi H;Nakao R;Katakura K;Asada M;Kaneko O
疟原虫于1923年首次在安哥拉的一只山羊身上被发现，直到最近才通过从赞比亚的一只山羊血液样本中分离出DNA来鉴定。大约10，000年前，山羊首次在新月沃地被驯化，现在分布在全球。目前尚不清楚在非洲山羊中发现的疟原虫是否起源于当地有蹄类动物中的寄生虫，或者它是否在山羊驯化之前在山羊中共同进化。为了解决这个问题，我们使用从非洲的苏丹和肯尼亚、西亚的伊朗以及东南亚的缅甸和泰国收集的总共1,299份山羊血液样本进行了基于PCR的监测。在所有地点都检测到疟原虫DNA，表明这种寄生虫不仅限于非洲，而且分布广泛。整个线粒体DNA序列显示，只有一个核苷酸之间的替代赞比亚/肯尼亚样本和其他人，支持存在一个山羊特异性疟原虫物种，推测疟原虫capillary，而不是感染当地的有蹄类疟疾寄生虫的山羊。我们还提出了第一张来自肯尼亚山羊样本的P. captain的照片。
Plasmodium was first identified in a goat in Angola in 1923, and only recently characterized by DNA isolation from a goat blood sample in Zambia. Goats were first domesticated in the Fertile Crescent approximately 10,000 years ago, and are now globally distributed. It is not known if the Plasmodium identified in African goats originated from parasites circulating in the local ungulates, or if it co-evolved in the goat before its domestication. To address this question, we performed PCR-based surveillance using a total of 1,299 goat blood samples collected from Sudan and Kenya in Africa, Iran in west Asia, and Myanmar and Thailand in southeast Asia. Plasmodium DNA was detected from all locations, suggesting that the parasite is not limited to Africa, but widely distributed. Whole mitochondrial DNA sequences revealed that there was only one nucleotide substitution between Zambian/Kenyan samples and others, supporting the existence of a goat-specific Plasmodium species, presumably Plasmodium caprae, rather than infection of goats by local ungulate malaria parasites. We also present the first photographic images of P. caprae, from one Kenyan goat sample.
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解开疟疾寄生虫。
影响因子：
4.6
作者：
Templeton TJ;Asada M;Jiratanh M;Ishikawa SA;Tiawsirisup S;Sivakumar T;Namangala B;Takeda M;Mohkaew K;Ngamjituea S;Inoue N;Sugimoto C;Inagaki Y;Suzuki Y;Yokoyama N;Kaewthamasorn M;Kaneko O
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通讯作者：
Paupy C
影响因子：
3
作者：
Soleimani-Ahmadi M;Vatandoost H;Zare M;Alizadeh A;Salehi M
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Salehi M
DOI：
10.1016/j.ijppaw.2018.01.001
发表时间：
2018-04
期刊：
International journal for parasitology. Parasites and wildlife
影响因子：
--
作者：
Asada M;Takeda M;Tomas WM;Pellegrin A;de Oliveira CHS;Barbosa JD;da Silveira JAG;Braga ÉM;Kaneko O
通讯作者：
Kaneko O