A common anterior insula representation of disgust observation, experience and imagination shows divergent functional connectivity pathways.
A common anterior insula representation of disgust observation, experience and imagination shows divergent functional connectivity pathways.
复制标题
DOI：
10.1371/journal.pone.0002939
复制
发表时间：
2008-08-13
期刊：
影响因子：
3.7
通讯作者：
Keysers C
中科院分区：
文献类型：
--
作者：
Jabbi M;Bastiaansen J;Keysers C
当我们想象、观察和执行一个动作时，会涉及到类似的大脑区域。情感也是如此吗？在这里，相同的受试者在（a）体验、（b）观看其他人体验以及（c）想象体验味觉情绪（通过脚本驱动的图像）时被扫描。利用扫描仪环境中厌恶感反复诱发的事实，我们扫描了相同的参与者，同时他们（a）观看演员品尝杯子中的内容并看起来很厌恶（b）品尝令人不快的苦味液体以诱发厌恶，以及（c）阅读并想象涉及厌恶及其中性对应物的场景。为了减少习惯，我们在所有三个扫描实验中混合了积极情绪的试验。我们发现前脑岛和相邻额叶盖中的体素涉及所有三种厌恶模式，这表明在社会感知和厌恶心理意象背景下的模拟具有共同的神经基质。然而，通过有效的连接，发现这个共享区域在三种模式中嵌入了不同的功能回路中，这表明为什么观察、想象和体验情绪的感觉如此不同。
Similar brain regions are involved when we imagine, observe and execute an action. Is the same true for emotions? Here, the same subjects were scanned while they (a) experience, (b) view someone else experiencing and (c) imagine experiencing gustatory emotions (through script-driven imagery). Capitalizing on the fact that disgust is repeatedly inducible within the scanner environment, we scanned the same participants while they (a) view actors taste the content of a cup and look disgusted (b) tasted unpleasant bitter liquids to induce disgust, and (c) read and imagine scenarios involving disgust and their neutral counterparts. To reduce habituation, we inter-mixed trials of positive emotions in all three scanning experiments. We found voxels in the anterior Insula and adjacent frontal operculum to be involved in all three modalities of disgust, suggesting that simulation in the context of social perception and mental imagery of disgust share a common neural substrates. Using effective connectivity, this shared region however was found to be embedded in distinct functional circuits during the three modalities, suggesting why observing, imagining and experiencing an emotion feels so different.
登录
查看更多内容
影响因子：
2.5
作者：
Adolphs, R;Tranel, D;Damasio, AR
通讯作者：
Damasio, AR
影响因子：
3.7
作者：
DIMBERG, U
通讯作者：
DIMBERG, U
影响因子：
25
作者：
Damasio, AR;Grabowski, TJ;Hichwa, RD
通讯作者：
Hichwa, RD
影响因子：
3.7
作者：
Gerardin, E;Sirigu, A;Le Bihan, D
通讯作者：
Le Bihan, D
影响因子：
3.7
作者：
Gray, Marcus A.;Harrison, Neil A.;Wiens, Stefan;Critchley, Hugo D.
通讯作者：
Critchley, Hugo D.