Electrochemical diagnostics of infectious viral diseases: Trends and challenges.
Electrochemical diagnostics of infectious viral diseases: Trends and challenges.
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DOI：
10.1016/j.bios.2021.113112
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发表时间：
2021-05-15
影响因子：
12.6
通讯作者：
Gobi KV
中科院分区：
文献类型：
--
作者：
Goud KY;Reddy KK;Khorshed A;Kumar VS;Mishra RK;Oraby M;Ibrahim AH;Kim H;Gobi KV
由病毒引起的传染病可以升级为影响全球人口和正常生活功能的不希望的大流行状况。这些反过来又影响了既定的世界经济，造成失业情况，身体，精神和情感压力，并挑战人类的生存。因此，及时发现、治疗、隔离和防止大流行性传染病传播到起源城镇以外是避免全球生命损害的关键（例如，冠状病毒病- 2019年，COVID-19）。这篇综述文章的目的是强调12种威胁生命的病毒的电化学诊断的最新进展，即COVID-19，中东呼吸综合征（MERS），严重急性呼吸综合征（SARS），流感，肝炎，人类免疫缺陷病毒（HIV），人乳头瘤病毒（HPV），寨卡病毒，单纯疱疹病毒，基孔肯雅病毒，登革热和轮状病毒。这篇评论介绍了设计，原则，基本原理，受体，和机制方面的传感器系统报告的此类病毒。将包含抗体或适体或识别基质中的直接/介导的电子转移的电化学传感器系统明确地分离成单独的子部分用于关键比较。这篇综述强调了将实验室研究转化为现实世界设备应用所面临的挑战，用于病毒检测的电化学诊断设备的未来前景和商业化方面。本文介绍了电化学传感器的研究背景和进展，以期为电化学传感器的设计和制造提供参考。
Infectious diseases caused by viruses can elevate up to undesired pandemic conditions affecting the global population and normal life function. These in turn impact the established world economy, create jobless situations, physical, mental, emotional stress, and challenge the human survival. Therefore, timely detection, treatment, isolation and prevention of spreading the pandemic infectious diseases not beyond the originated town is critical to avoid global impairment of life (e.g., Corona virus disease - 2019, COVID-19). The objective of this review article is to emphasize the recent advancements in the electrochemical diagnostics of twelve life-threatening viruses namely - COVID-19, Middle east respiratory syndrome (MERS), Severe acute respiratory syndrome (SARS), Influenza, Hepatitis, Human immunodeficiency virus (HIV), Human papilloma virus (HPV), Zika virus, Herpes simplex virus, Chikungunya, Dengue, and Rotavirus. This review describes the design, principle, underlying rationale, receptor, and mechanistic aspects of sensor systems reported for such viruses. Electrochemical sensor systems which comprised either antibody or aptamers or direct/mediated electron transfer in the recognition matrix were explicitly segregated into separate sub-sections for critical comparison. This review emphasizes the current challenges involved in translating laboratory research to real-world device applications, future prospects and commercialization aspects of electrochemical diagnostic devices for virus detection. The background and overall progress provided in this review are expected to be insightful to the researchers in sensor field and facilitate the design and fabrication of electrochemical sensors for life-threatening viruses with broader applicability to any desired pathogens.
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影响因子：
4.3
作者：
Bosserdt, Maria;Gajovic-Eichelman, Nenad;Scheller, Frieder W.
通讯作者：
Scheller, Frieder W.
影响因子：
7.3
作者：
Cao P;Wang Z;Yan AW;McVernon J;Xu J;Heffernan JM;Kedzierska K;McCaw JM
通讯作者：
McCaw JM
影响因子：
6
作者：
Asran, Aml M.;Mohamed, Mona A.;Allam, Nageh K.
通讯作者：
Allam, Nageh K.
影响因子：
3
作者：
Attar, Aisha;Mandli, Jihane;Amine, Aziz
通讯作者：
Amine, Aziz
影响因子：
8.4
作者：
Chekin, Fereshteh;Bagga, Komal;Szunerits, Sabine
通讯作者：
Szunerits, Sabine