Chromosomal rearrangements and karyotype evolution in carnivores revealed by chromosome painting.

Chromosomal rearrangements and karyotype evolution in carnivores revealed by chromosome painting.
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DOI:
10.1038/hdy.2011.107
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发表时间:
2012-01
期刊:
影响因子:
3.8
通讯作者:
Yang, F.
Yang, F.
中科院分区:
生物学2区
文献类型:
--
作者:
Nie, W.;Wang, J.;Su, W.;Wang, D.;Tanomtong, A.;Perelman, P. L.;Graphodatsky, A. S.;Yang, F.

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食肉动物的染色体进化已经被广泛地使用跨物种染色体彩绘重新审视。绘画探针来自流动分选染色体的家犬,其中有一个最重排的核型在哺乳动物和最高的dipoid数(2n=78)的食肉动物,是一个强大的工具,在检测进化内和染色体间重排。然而,只有少数比较地图已建立狗和其他非犬科物种之间。在这里,我们将狗探针的跨物种绘画扩展到代表六个食肉动物家族的另外七个物种:欧亚猞猁(Lynx lynx)、石貂(Martes foina)、小印度果子狸(Viverricula indica)、亚洲棕榈果子狸(Paradoxurus hermaphrodites)、爪哇猫鼬(Hepestes javanicas)、浣熊(Procyon lotor)和大熊猫(Ailuropoda melanoleuca)。染色体内重排的数量和位置被发现在这些食肉动物物种之间存在差异。建立了人与石貂的比较图,以及长江江豚、石貂与人的比较图,以便于进行外群比较,并将石貂与其他食肉动物的比较图与人与其他物种的比较图整合起来。这些比较图谱使食肉动物的基因组进化和核型系统发育关系有了进一步的了解,并将有助于将人类、家犬和猫的基因图谱数据转移到其他物种。
Chromosomal evolution in carnivores has been revisited extensively using cross-species chromosome painting. Painting probes derived from flow-sorted chromosomes of the domestic dog, which has one of the most rearranged karyotypes in mammals and the highest dipoid number (2n=78) in carnivores, are a powerful tool in detecting both evolutionary intra- and inter-chromosomal rearrangements. However, only a few comparative maps have been established between dog and other non-Canidae species. Here, we extended cross-species painting with dog probes to seven more species representing six carnivore families: Eurasian lynx (Lynx lynx), the stone marten (Martes foina), the small Indian civet (Viverricula indica), the Asian palm civet (Paradoxurus hermaphrodites), Javan mongoose (Hepestes javanicas), the raccoon (Procyon lotor) and the giant panda (Ailuropoda melanoleuca). The numbers and positions of intra-chromosomal rearrangements were found to differ among these carnivore species. A comparative map between human and stone marten, and a map among the Yangtze finless porpoise (Neophocaena phocaenoides asiaeorientalis), stone marten and human were also established to facilitate outgroup comparison and to integrate comparative maps between stone marten and other carnivores with such maps between human and other species. These comparative maps give further insight into genome evolution and karyotype phylogenetic relationships among carnivores, and will facilitate the transfer of gene mapping data from human, domestic dog and cat to other species.
DOI: 10.1023/a:1015292005631
发表时间: 2002-03-01
影响因子: 2.6
作者:
Nie, WH;Wang, JH;Yang, FT
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发表时间: 2001-01-01
期刊: CYTOGENETICS AND CELL GENETICS
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发表时间: 2000-10-01
期刊: MAMMALIAN GENOME
影响因子: 2.5
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发表时间: 2009-04-01
影响因子: 2.6
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发表时间: 2000-01-01
期刊: CYTOGENETICS AND CELL GENETICS
影响因子: --
作者:
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通讯作者: Ferguson-Smith, MA