Large-Scale Silica Overcoating of Gold Nanorods with Tunable Shell Thicknesses.
Large-Scale Silica Overcoating of Gold Nanorods with Tunable Shell Thicknesses.
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DOI：
10.1021/cm504764v
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发表时间：
2015-04-28
影响因子：
8.6
通讯作者：
Tracy, Joseph B.
中科院分区：
文献类型：
--
作者：
Wu, Wei-Chen;Tracy, Joseph B.
包覆SiO2的金纳米棒（gnr）在光热加热过程中可增强其形状稳定性，并可与硅烷进一步功能化，并可用于生物医学应用。虽然近年来已经有了大规模合成gnr的方法，但gnr的SiO2复涂仍然是在小反应规模上进行的。在这里，我们报告了一种大规模合成SiO2-overcoated GNRs （SiO2-GNRs）的方法，该方法可以得到~ 190 mg的SiO2-GNRs。通过注射泵加入四乙氧基硅烷（TEOS）来稳定gnr， SiO2被沉积在十六烷基三甲基溴化铵（CTAB）涂层上并包封。控制CTAB的浓度对于获得均匀的覆盖层至关重要。sio2 - gnr的光学吸收光谱与未包覆的gnr非常相似，这表明单gnr而不是多个gnr被包覆，并证实了它们保持了良好的分散。通过调整反应条件，可以得到厚度为~ 20 nm的壳层。对于薄壳（<10 nm），在复涂反应期间的不同时间添加聚（乙二醇）硅烷（peg -硅烷）可以轻松控制壳厚度，使壳薄至2 nm。庞大的PEG链终止了进一步交联和SiO2的沉积。
Gold nanorods (GNRs) overcoated with SiO2 are of interest for enhancing the shape stability of GNRs during photothermal heating, for further functionalization with silanes, and for biomedical applications. While methods have recently been developed for synthesizing GNRs on a large scale, SiO2 overcoating of GNRs is still conducted on a small reaction scale. Here, we report a method for large-scale synthesis of SiO2-overcoated GNRs (SiO2-GNRs), which gives ∼190 mg of SiO2-GNRs. SiO2 is deposited onto and encapsulates the cetyltrimethylammonium bromide (CTAB) coatings that stabilize GNRs by adding tetraethoxysilane (TEOS) via syringe pump. Control over the CTAB concentration is critically important for obtaining uniform overcoatings. Optical absorbance spectra of SiO2-GNRs closely resemble those of uncoated GNRs, which indicates overcoating of single rather than multiple GNRs and confirms that they remain well dispersed. By adjusting the reaction conditions, shells as thick as ∼20 nm can be obtained. For thin shells (<10 nm), addition of poly(ethylene glycol) silane (PEG-silane) at different times during the overcoating reaction allows facile control over the shell thickness, giving shells as thin as ∼2 nm. The bulky PEG chain terminates further cross-linking and deposition of SiO2.
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影响因子：
7.4
作者：
Cifuentes, A;Bernal, JL;DiezMasa, JC
通讯作者：
DiezMasa, JC
叶酸共轭二氧化硅修饰的金纳米棒用于 X 射线/CT 成像引导的双模辐射和光热治疗
影响因子：
14
作者：
Huang, Peng;Bao, Le;Cui, Daxiang
通讯作者：
Cui, Daxiang
影响因子：
6.6
作者：
Chen, Xin;Cheng, Xiaoyu;Gooding, J. Justin
通讯作者：
Gooding, J. Justin
DOI：
10.1016/j.colsurfa.2012.06.003
发表时间：
2012-09-05
影响因子：
5.2
作者：
Huang, Chia-Chi;Huang, Chen-Han;Yang, Tzzy-Schiuan
通讯作者：
Yang, Tzzy-Schiuan
影响因子：
3.5
作者：
Chen, Leng-Chun;Wei, Chen-Wei;Lo, Leu-Wei
通讯作者：
Lo, Leu-Wei