The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review.
The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review.
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DOI：
10.1186/s13102-022-00397-2
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发表时间：
2022-01-06
期刊：
影响因子：
--
通讯作者：
Millar NL
中科院分区：
文献类型：
--
作者：
Docherty S;Harley R;McAuley JJ;Crowe LAN;Pedret C;Kirwan PD;Siebert S;Millar NL
体育锻炼的生理效应被普遍报道为有益于心血管和肌肉骨骼系统。医疗专业人员广泛提倡锻炼，以帮助身体和情绪健康;然而，实现这一目标的机制却不太清楚。尽管有许多有益的属性，但某些类型的运动会造成显著的生理压力。一些研究证明了运动和免疫激活之间的关键关系。先天免疫系统的激活响应于运动而发生，并且提出这在很大程度上由细胞因子信号传导介导。细胞因子通常根据其炎症特性进行分类，并且证据表明，响应于运动而表达的细胞因子是多种多样的，并且可以起到传播、调节或减轻肌肉骨骼健康中的炎症的作用。本文综述了运动与免疫系统之间关系的现有文献，重点是运动诱导的细胞因子表达如何调节炎症和免疫反应。
The physiological effects of physical exercise are ubiquitously reported as beneficial to the cardiovascular and musculoskeletal systems. Exercise is widely promoted by medical professionals to aid both physical and emotional wellbeing; however, mechanisms through which this is achieved are less well understood. Despite numerous beneficial attributes, certain types of exercise can inflict significant significant physiological stress. Several studies document a key relationship between exercise and immune activation. Activation of the innate immune system occurs in response to exercise and it is proposed this is largely mediated by cytokine signalling. Cytokines are typically classified according to their inflammatory properties and evidence has shown that cytokines expressed in response to exercise are diverse and may act to propagate, modulate or mitigate inflammation in musculoskeletal health. The review summarizes the existing literature on the relationship between exercise and the immune system with emphasis on how exercise-induced cytokine expression modulates inflammation and the immune response.
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影响因子：
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作者：
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DOI：
10.1097/ij9.0000000000000017
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