Influence of chronic endurance exercise training on conduit artery retrograde and oscillatory shear in older adults.
Influence of chronic endurance exercise training on conduit artery retrograde and oscillatory shear in older adults.
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慢性耐力运动训练对老年人导管逆行和振荡剪切的影响。
DOI：
10.1007/s00421-016-3445-4
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发表时间：
2016-10
影响因子：
3
通讯作者：
Ueda K
中科院分区：
文献类型：
--
作者：
Casey DP;Schneider AC;Ueda K
随着年龄的增长，人类外周导管动脉中的逆行剪切力和振荡剪切力往往会增加。剪切率的增加是由于衰老过程还是由于通常伴随衰老的不太活跃的生活方式的影响尚不清楚。因此，我们研究了长期耐力运动训练是否会减弱老年人的导管动脉逆行和振荡剪切力。在静息条件下通过多普勒超声确定肱动脉和股总动脉的平均血流速度和直径，并计算 13 名年轻人（24±2 岁）、17 名未经训练的老年人（66±3 岁）和 16 名接受过耐力运动训练的老年人（66±7 岁）的剪切率。肱动脉逆行剪切力（−9.1 ± 6.4 vs. -12.6 ± 9.4 s−1；P = 0.35）和振荡剪切力（0.14 ± 0.08 vs. 0.14 ± 0.08 任意单位；P = 0.99）在老年训练组和未训练组之间相似，而肱动脉逆行剪切力和振荡剪切力在老年未训练组中比年轻人更大（−5.0 ± 3.4、0.08 ± 0.05 s−1 任意单位，P 分别 = 0.017 和 0.048）。年轻和年长训练过的肱骨逆行（P = 0.29）和振荡（P = 0.07）剪切力之间没有差异。与未受过训练的老年组相比，受过训练的老年组的股总动脉逆行（−6.3 ± 2.9 s−1）和振荡（0.21 ± 0.08 任意单位）剪切力降低（−10.4 ± 4.1 和 0.30 ± 0.09 s−1 任意单位，分别 P = 0.005 和 0.006），但与年轻人相似（−7.1 ± 4.1 和 0.30 ± 0.09 s−1 任意单位），但与年轻人相似（−7.1 ± 3.5 和 0.19 ± 0.06 s−1 任意单位，P 分别 = 0.81 和 0.87）。我们的结果表明，老年人的长期耐力运动训练可以改善逆行和振荡剪切率模式，特别是在股总动脉中。
With aging, there tends to be an increase in retrograde and oscillatory shear in peripheral conduit arteries of humans. Whether the increase in shear rate is due to the aging process or an effect of a less active lifestyle that often accompanies aging is unknown. Therefore, we examined whether chronic endurance exercise training attenuates conduit artery retrograde and oscillatory shear in older adults. Brachial and common femoral artery mean blood velocities and diameter were determined via Doppler ultrasound under resting conditions, and shear rate was calculated in 13 young (24 ± 2 years), 17 older untrained (66 ± 3 years), and 16 older endurance exercise-trained adults (66 ± 7 years). Brachial artery retrograde (−9.1 ± 6.4 vs. −12.6 ± 9.4 s−1; P = 0.35) and oscillatory (0.14 ± 0.08 vs. 0.14 ± 0.08 arbitrary units; P = 0.99) shear were similar between the older trained and untrained groups, whereas brachial artery retrograde and oscillatory shear were greater in older untrained compared to young adults (−5.0 ± 3.4, 0.08 ± 0.05 s−1 arbitrary units, P = 0.017 and 0.048, respectively). There was no difference between the young and older trained brachial retrograde (P = 0.29) and oscillatory (P = 0.07) shear. Common femoral artery retrograde (−6.3 ± 2.9 s−1) and oscillatory (0.21 ± 0.08 arbitrary units) shear were reduced in older trained compared to the older untrained group (−10.4 ± 4.1 and 0.30 ± 0.09 s−1 arbitrary units, both P = 0.005 and 0.006, respectively), yet similar to young adults (−7.1 ± 3.5 and 0.19 ± 0.06 s−1 arbitrary units, P = 0.81 and 0.87, respectively). Our results suggest that chronic endurance exercise training in older adults ameliorates retrograde and oscillatory shear rate patterns, particularly in the common femoral artery.
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DOI：
10.1161/hypertensionaha.110.165365
发表时间：
2011-03
期刊：
Hypertension (Dallas, Tex. : 1979)
影响因子：
--
作者：
Padilla J;Simmons GH;Fadel PJ;Laughlin MH;Joyner MJ;Casey DP
通讯作者：
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影响因子：
4.5
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DOI：
10.1152/ajpheart.00713.2009
发表时间：
2010-05-01
影响因子：
4.8
作者：
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通讯作者：
Leuenberger, Urs A.
影响因子：
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作者：
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