Uremic anorexia and gastrointestinal motility dysfunction correlate with the changes of ghrelin system in hypothalamus

Uremic anorexia and gastrointestinal motility dysfunction correlate with the changes of ghrelin system in hypothalamus
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尿毒症厌食、胃肠动力功能障碍与下丘脑ghrelin系统变化相关

DOI:
10.1111/nep.12015
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发表时间:
2013-02
期刊:
Nephrology (Carlton)
影响因子:
--
通讯作者:
Xue RL
Xue RL
中科院分区:
其他
文献类型:
--
作者:
Fu RG;Ge H;Yao GL;Wang L;Zhu D;Ren ST;Ma LQ;Xue RL

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Ghrelin可作为启动进食的信号,并通过下丘脑环路参与胃肠运动的调节。本研究探讨慢性肾功能衰竭(CRF)大鼠下丘脑Ghrelin系统变化与胃肠动力障碍和厌食的关系。
Ghrelin can act as a signal for meal initiation and play a role in the regulation of gastrointestinal (GI) motility via hypothalamic circuit. This study investigated the correlation between changes of hypothalamic ghrelin system and GI motility dysfunction and anorexia in rats with chronic renal failure (CRF).
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