The influence of different restorative materials on secondary caries development in situ.
The influence of different restorative materials on secondary caries development in situ.
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DOI：
10.1016/j.jdent.2014.07.003
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发表时间：
2014-09
影响因子：
4.4
通讯作者：
Huysmans MC
中科院分区：
文献类型：
--
作者：
van de Sande FH;Opdam NJ;Truin GJ;Bronkhorst EM;de Soet JJ;Cenci MS;Huysmans MC
直接修复材料对龋齿形成的影响通过8周的裂口设计原位研究进行了调查，验证了不同复合基材料和汞合金在修复后的矿物质损失没有差异的假设。采用汞合金、微杂化材料、纳米杂化材料和硅烷复合材料制备牙本质修复体6组（n=18）。除了硅烷基团（silorane - System-Adhesive）外，复合材料与含或不含抗菌单体的体系（分别为Clearfil-SE-Protect和Clearfil-SE-bond）进行粘接。未修复的牙本质样本作为对照（原发性龋）。将样品插入专门为实验制作的下假体的槽中。受试者被指示将下假体浸入蔗糖溶液中，每天4次。在基线和8周时，对样品进行口服外放射照相，并计算综合矿物质损失。数据采用多元线性回归，采用多水平模型进行统计学分析（p=0.05）。选择9名受试者，仅观察外病变。这一假设被部分否定，因为与抗菌体系结合的微杂化复合材料和纳米杂化复合材料与汞合金相比，矿物质损失具有统计学意义上的显著降低。此外，与对照组相比，这些组没有明显差异。在本研究范围内，修复材料可能会影响外部病变的进展。与复合材料相比，在原位放置8周后，汞合金与牙本质下部继发龋的进展没有关系。
The effect of direct restorative materials on caries lesion formation was investigated with an 8-week in situ study with split-mouth design, testing the hypothesis that no difference in mineral loss next to a restoration would be found between different composite-based-materials and amalgam. Six groups (n=18) of restored dentin samples were prepared using amalgam, a microhybrid, a nanohybrid and a silorane composite. The composites were adhesively bonded with systems with or without an antibacterial monomer (Clearfil-SE-Protect, Clearfil-SE-bond, respectively), except for the silorane group (Silorane- System-Adhesive). Non-restored dentin samples were used as control (primary caries). Samples were inserted into slots, in lower prosthesis especially made for the experiment. Subjects were instructed to dip the lower prosthesis in a sucrose solution 4 times per day. At baseline and 8 weeks, samples were radiographed extra-orally and the integrated mineral loss was calculated. Data were statistically analyzed using multiple linear regression with a multilevel model (p=0.05). Nine subjects were selected, and only outer lesions were observed. The hypothesis was partially rejected, as the microhybrid composite bonded with the antibacterial system and the nanohybrid composite presented statistically significant lower mineral loss compared to amalgam. Also, no significant differences were seen for these groups compared to control. Within the limits of this study, the restorative material may influence outer lesion progression. Amalgam was not found to be related to lower secondary caries progression in dentin compared to composite-based materials after 8 weeks in situ.
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影响因子：
5
作者：
Lien, Wen;Vandewalle, Kraig S.
通讯作者：
Vandewalle, Kraig S.
影响因子：
5
作者：
Imazato, S;Kuramoto, A;Peters, MC
通讯作者：
Peters, MC
影响因子：
4.2
作者：
HALS, E;ANDREASSEN, BH;BIE, T
通讯作者：
BIE, T
影响因子：
7.6
作者：
Opdam, N. J. M.;Bronkhorst, E. M.;Huysmans, M. -C. D. N. J. M.
通讯作者：
Huysmans, M. -C. D. N. J. M.
影响因子：
4.2
作者：
Thomas, R. Z.;Ruben, J. L.;Huysmans, M. C. D. N. J. M.
通讯作者：
Huysmans, M. C. D. N. J. M.