A central role for the lateral prefrontal cortex in goal-directed and stimulus-driven attention.

A central role for the lateral prefrontal cortex in goal-directed and stimulus-driven attention.
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DOI:
10.1038/nn.2509
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发表时间:
2010-04
影响因子:
25
通讯作者:
Marois, Rene
Marois, Rene
中科院分区:
医学1区
文献类型:
--
作者:
Asplund, Christopher L.;Todd, J. Jay;Snyder, Andy P.;Marois, Rene

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注意力选择哪些感觉信息优先被处理,并最终进入我们的意识。然而,注意力不是一个单一的过程:它可以被意外的或显著的事件所吸引(刺激驱动),也可以在自主控制下被调配(目标导向),并且这两种形式的注意力主要由不同的腹侧和背侧顶额网络来实现。然而,为了产生连贯的行为和意识,刺激驱动和目标导向的行为最终必须相互作用。在这里我们表明,腹侧网络(而非背侧网络)能够解释刺激驱动的注意力对有意识感知的限制,并且在该网络的外侧前额叶部分,刺激驱动和目标导向的注意力汇聚在一起。尽管这些结果在存在目标导向的任务需求时,并不排除背侧网络参与意识活动,但它们指出了外侧前额叶皮层在注意力和意识控制中的一般作用。
Attention selects which sensory information is preferentially processed and ultimately reaches our awareness. Attention, however, is not a unitary process: It can be captured by unexpected or salient events (stimulus-driven) or it can be deployed under voluntary control (goal-directed), and these two forms of attention are implemented by largely distinct ventral and dorsal parieto-frontal networks. Yet, for coherent behavior and awareness to emerge, stimulus-driven and goal-directed behavior must ultimately interact. Here we show that the ventral, but not dorsal, network can account for stimulus-driven attentional limits to conscious perception, and that it is in the lateral prefrontal component of that network where stimulus-driven and goal-directed attention converge. Although these results do not rule out dorsal network involvement in awareness when goal-directed task demands are present, they point to a general role for the lateral prefrontal cortex in the control of attention and awareness.
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