Transposable element islands facilitate adaptation to novel environments in an invasive species.
Transposable element islands facilitate adaptation to novel environments in an invasive species.
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DOI：
10.1038/ncomms6495
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发表时间：
2014-12-16
影响因子：
16.6
通讯作者：
Oettler, Jan
中科院分区：
文献类型：
--
作者：
Schrader, Lukas;Kim, Jay W.;Ence, Daniel;Zimin, Aleksey;Klein, Antonia;Wyschetzki, Katharina;Weichselgartner, Tobias;Kemena, Carsten;Stoekl, Johannes;Schultner, Eva;Wurm, Yannick;Smith, Christopher D.;Yandell, Mark;Heinze, Juergen;Gadau, Juergen;Oettler, Jan
适应需要遗传变异，但创始人群体通常是遗传枯竭。在这里，我们序列的两个种群的近交蚂蚁，分歧的表型，以确定如何产生变异。暗枝蚁的基因组序列最小，它的结构表明转座因子（TE）在适应性进化中起着重要作用。在单核苷酸变异、基因/外显子重复和缺失以及基因同源性方面，占基因组7.18%的TE（TE岛）的积累比其他区域进化得更快。一个非随机分布的基因家族，幼虫/成人特定的基因表达和差异甲基化的TE岛的迹象表明基因组内的差异调节，进化速率和合并的有效人口规模。我们的研究揭示了入侵物种的TE，生活史和适应之间的三方相互作用。 遗传变异是物种进化的关键。在这里，作者测序两个表型不同的群体的蚂蚁concondyla obscurior，并发现积累的转座因子与遗传变异，可能有一个分化，适应和物种形成的作用。
Adaptation requires genetic variation, but founder populations are generally genetically depleted. Here we sequence two populations of an inbred ant that diverge in phenotype to determine how variability is generated. Cardiocondyla obscurior has the smallest of the sequenced ant genomes and its structure suggests a fundamental role of transposable elements (TEs) in adaptive evolution. Accumulations of TEs (TE islands) comprising 7.18% of the genome evolve faster than other regions with regard to single-nucleotide variants, gene/exon duplications and deletions and gene homology. A non-random distribution of gene families, larvae/adult specific gene expression and signs of differential methylation in TE islands indicate intragenomic differences in regulation, evolutionary rates and coalescent effective population size. Our study reveals a tripartite interplay between TEs, life history and adaptation in an invasive species. Genetic variation is key to species evolution. Here the authors sequence two phenotypically distinct populations of the ant Cardiocondyla obscurior, and find accumulations of transposable elements correlating with genetic variation that may have a role in differentiation, adaptation and speciation.
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影响因子：
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作者：
Bohbot, J.;Pitts, R. J.;Zwiebel, L. J.
通讯作者：
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影响因子：
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通讯作者：
Smith, Christopher D.