Standardised mindfulness-based interventions in healthcare: an overview of systematic reviews and meta-analyses of RCTs.

Standardised mindfulness-based interventions in healthcare: an overview of systematic reviews and meta-analyses of RCTs.
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DOI:
10.1371/journal.pone.0124344
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发表时间:
2015
期刊:
影响因子:
3.7
通讯作者:
Hunink MG
Hunink MG
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Gotink RA;Chu P;Busschbach JJ;Benson H;Fricchione GL;Hunink MG

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正念疗法被广泛用于治疗和预防各种常见慢性疾病,尽管对不同患者类别的有效性缺乏共识。系统回顾MBSR和MBCT在不同患者类别中的有效性证据。对随机对照试验的系统评价和荟萃分析,使用标准化的正念减压或正念减压项目。我们使用PRISMA指南来评估纳入的综述的质量,并使用主要结局指标Cohen’s d进行随机效应荟萃分析。所有类型的参与者都被考虑在内。搜索产生了187篇评论:包括23篇,涵盖了115个独特的随机对照试验和8683个不同条件的独特个体。与等候名单对照和常规治疗相比,MBSR和MBCT显著改善了抑郁症状(d=0.37; 95%CI 0.28至0.45,基于5篇综述,N=2814)、焦虑(d=0.49; 95%CI 0.37至0.61,基于4篇综述,N=2525)、压力(d=0.51; 95%CI 0.36至0.67,基于2篇综述,N=1570)、生活质量(d=0.39; 95%CI 0.08至0.70,基于2篇综述,N=511)和身体功能(d=0.27; 95%CI 0.12至0.42,基于3篇综述,N=1015)。局限性包括患者类别的异质性、发表偏倚的风险和一些研究中有限的长期随访。证据支持正念减压和正念ct在癌症、心血管疾病、慢性疼痛、抑郁、焦虑症的辅助治疗和健康成人和儿童的预防中缓解精神和身体症状。
Mindfulness-based therapies are being used in a wide range of common chronic conditions in both treatment and prevention despite lack of consensus about their effectiveness in different patient categories. To systematically review the evidence of effectiveness MBSR and MBCT in different patient categories. A systematic review and meta-analysis of systematic reviews of RCTs, using the standardized MBSR or MBCT programs. We used PRISMA guidelines to assess the quality of the included reviews and performed a random effects meta-analysis with main outcome measure Cohen’s d. All types of participants were considered. The search produced 187 reviews: 23 were included, covering 115 unique RCTs and 8,683 unique individuals with various conditions. Compared to wait list control and compared to treatment as usual, MBSR and MBCT significantly improved depressive symptoms (d=0.37; 95%CI 0.28 to 0.45, based on 5 reviews, N=2814), anxiety (d=0.49; 95%CI 0.37 to 0.61, based on 4 reviews, N=2525), stress (d=0.51; 95%CI 0.36 to 0.67, based on 2 reviews, N=1570), quality of life (d=0.39; 95%CI 0.08 to 0.70, based on 2 reviews, N=511) and physical functioning (d=0.27; 95%CI 0.12 to 0.42, based on 3 reviews, N=1015). Limitations include heterogeneity within patient categories, risk of publication bias and limited long-term follow-up in several studies. The evidence supports the use of MBSR and MBCT to alleviate symptoms, both mental and physical, in the adjunct treatment of cancer, cardiovascular disease, chronic pain, depression, anxiety disorders and in prevention in healthy adults and children.
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