Meditative therapies for reducing anxiety: a systematic review and meta-analysis of randomized controlled trials.
Meditative therapies for reducing anxiety: a systematic review and meta-analysis of randomized controlled trials.
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DOI：
10.1002/da.21964
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发表时间：
2012-07
影响因子：
7.4
通讯作者：
Lejuez, C. W.
中科院分区：
文献类型：
--
作者：
Chen, Kevin W.;Berger, Christine C.;Manheimer, Eric;Forde, Darlene;Magidson, Jessica;Dachman, Laya;Lejuez, C. W.
焦虑症是最常见的精神疾病之一;焦虑症患者经常寻求冥想疗法作为补充疗法。虽然有多篇关于冥想对健康的益处的评论，但没有一篇评论专门关注冥想对焦虑的疗效。主要的医学数据库进行了彻底搜索与各种类型的冥想和焦虑相关的关键字。筛选了1000多篇摘要，审查了200多篇全文。仅纳入RCT。使用Boutron（2005）评价非药物试验报告的检查表（CLEAR-NPT）评估研究质量;联系90%的作者以获取更多信息。使用Review Manager 5进行荟萃分析。荟萃分析共纳入36项RCT（2，466项观察结果）。大多数随机对照试验在焦虑作为次要问题的患者中进行。在0.0-1.0量表上，研究质量范围为0.3 - 1.0（平均值= 0.72）。与等待列表控制组相比，标准化均值差（SMD）为-0.52（p <0.001; 25项随机对照试验），与注意力控制组相比为-0.59（p <0.001; 7项随机对照试验），与替代治疗组相比为-0.27（p < 0.01; 10项随机对照试验）。25项研究报告了冥想组与对照组相比在统计学上的上级结果。未报告不良反应。本文综述了冥想疗法在减轻焦虑症状方面的一些疗效，这对应用冥想技术治疗焦虑具有重要的临床意义。然而，大多数研究仅测量焦虑症状的改善，而不是临床诊断的焦虑症。
Anxiety disorders are among the most common psychiatric disorders; meditative therapies are frequently sought by patients with anxiety as a complementary therapy. Although multiple reviews exist on the general health benefits of meditation, no review has been focused on the efficacy of meditation for anxiety specifically. Major medical databases were searched thoroughly with keywords related to various types of meditation AND anxiety. Over 1000 abstracts were screened, and 200+ full articles were reviewed. Only RCTs were included. The Boutron (2005) checklist to evaluate a report of a non-pharmaceutical trial (CLEAR-NPT) was used to assess study quality; 90% authors were contacted for additional information. Review Manager 5 was used for meta-analysis. A total of 36 RCTs were included in the meta-analysis (2,466 observations). Most RCTs were conducted among patients with anxiety as a secondary concern. The study quality ranged from 0.3 to 1.0 on the 0.0–1.0 scale (mean = 0.72). Standardized mean difference (SMD) was −0.52 in comparison with waiting-list control (p < .001; 25 RCTs), −0.59 in comparison with attention control (p < .001; 7 RCTs), and −0.27 in comparison with alternative treatments (p < 0.01; 10 RCTs). 25 studies reported statistically superior outcomes in the meditation group compared to control. No adverse effects were reported. This review demonstrates some efficacy of meditative therapies in reducing anxiety symptoms, which has important clinical implications for applying meditative techniques in treating anxiety. However, most studies measured only improvement in anxiety symptoms, but not anxiety disorders as clinically diagnosed.
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