Prevalence of measles, mumps, rubella, and varicella susceptibility among health science students in a University in India.

Prevalence of measles, mumps, rubella, and varicella susceptibility among health science students in a University in India.
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DOI:
10.1002/ajim.22046
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发表时间:
2013-01
影响因子:
3.5
通讯作者:
Sathiakumar, Nalini
Sathiakumar, Nalini
中科院分区:
医学4区
文献类型:
--
作者:
Arunkumar, G.;Vandana, K. E.;Sathiakumar, Nalini

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卫生科学专业的学生感染和传播病毒性疾病的风险增加,如麻疹、腮腺炎、风疹和水痘。本研究旨在确定HSS对这些感染的易感性。采用横断面设计,印度Manipal大学的790名HSS回答了一份问卷,并提供了一份血样,通过ELISA(Enclavynost ®)检测了麻疹、腮腺炎、风疹和水痘的特异性IgG抗体。研究组包括医学(53.9%),护理(16.6%)和专职医疗(29.5%)的学生。在790名儿童中,麻疹、腮腺炎、风疹和水痘的血清学易感率分别为9.5%、32.0%、16.6%和25.8%。麻疹、腮腺炎、风疹和水痘的易感性分别为7.9%、34.7%、10.7%和35.2%。对麻疹、腮腺炎、风疹和/或水痘易感的HSS在训练期间有感染这些疾病的风险。此外,它们可能是医院内传播的潜在来源,对免疫功能低下的患者构成风险。因此,在印度,HSS在进入医学院时应接种麻疹、腮腺炎、风疹和水痘疫苗。
Health science students (HSS) are at increased risk of contracting and transmitting viral disease such as measles, mumps, rubella and varicella (chickenpox). This study was undertaken to determine the prevalence of susceptibility of HSS to these infections. Using a cross-sectional design, 790 HSS of Manipal University, Manipal, India, answered a questionnaire and provided a blood sample which was tested for specific IgG antibodies to measles, mumps, rubella and varicella by ELISA (Enzygnost®). The study group was comprised of medical (53.9%), nursing (16.6%) and allied health (29.5%) students. Among the overall group (n=790), the prevalence of serological susceptibility to measles, mumps, rubella and varicella were 9.5%, 32.0%, 16.6%, and 25.8%, respectively. Among the subgroup of vaccinated subjects, susceptibility to measles, mumps, rubella and varicella were 7.9%, 34.7%, 10.7% and 35.2%, respectively. HSS susceptible to measles, mumps, rubella and/or varicella are at risk of acquiring these diseases during their training period. In addition, they may be a potential source for nosocomial transmission posing a risk to immunocompromised patients. Hence, in the Indian setting, HSS should be immunized against measles, mumps, rubella and varicella at the time of joining the medical school.
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