Intravital imaging.
Intravital imaging.
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DOI:
10.1016/j.cell.2011.11.004
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发表时间:
2011-11-23
期刊:
影响因子:
64.5
通讯作者:
Weissleder R
中科院分区:
文献类型:
--
作者:
Pittet MJ;Weissleder R
Until recently, the idea of observing life deep within the tissues of a living mouse, at a resolution sufficient to pick out cellular behaviors and molecular signals underlying them, remained a much-coveted dream. Now, a new era of intravital fluorescence microscopy has dawned. In this Primer, we review the technologies that made this revolution possible, and demonstrate how intravital imaging is beginning to provide quantitative and dynamic insights into cell biology, immunology, tumor biology and neurobiology.
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